Rebecca Drummond

2024

CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCII^hi interstitial lung macrophages

Mohamed, S. H., Vanhoffelen, E., Shun Fu, M., Hei Lau, P., Hain, S., Seldeslachts, L., Cosway, E., Anderson, G., McCulloch, L., Vande Velde, G. & Drummond, R. A., 20 Aug 2024, (E-pub ahead of print) In: Mucosal immunology.

Research output: Contribution to journal › Article › peer-review

Open Access

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4 Downloads (Pure)

Interferon-γ and IL-27 positively regulate type 1 regulatory T-cell development during adaptive tolerance

Lecky, D. A. J., Sheriff, L., Rouvray, S. T., George, L. S., Drummond, R. A., Wraith, D. C. & Bending, D., 26 Jun 2024, bioRxiv.

Research output: Working paper/Preprint › Preprint

2023

How metals fuel fungal virulence, yet promote anti-fungal immunity

Alselami, A. & Drummond, R. A., 31 Oct 2023, In: Disease Models & Mechanisms. 16, 10, 12 p., dmm050393.

Research output: Contribution to journal › Review article › peer-review

Open Access

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59 Downloads (Pure)

Microglia are not protective against cryptococcal meningitis

Mohamed, S. H., Fu, M. S., Hain, S., Alselami, A., Vanhoffelen, E., Li, Y., Bojang, E., Lukande, R., Ballou, E. R., May, R. C., Ding, C., Velde, G. V. & Drummond, R. A., 8 Nov 2023, In: Nature Communications. 14, 1, 15 p., 7202.

Research output: Contribution to journal › Article › peer-review

Open Access

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60 Downloads (Pure)

What fungal CNS infections can teach us about neuroimmunology and CNS-specific immunity

Drummond, R. A., 1 May 2023, In: Seminars in Immunology. 67, 7 p., 101751.

Research output: Contribution to journal › Review article › peer-review

Open Access

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58 Downloads (Pure)

2022

Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria

Drummond, R. A., Desai, J. V., Ricotta, E. E., Swamydas, M., Deming, C., Conlan, S., Quinones, M., Matei-Rascu, V., Sherif, L., Lecky, D., Lee, C-C. R., Green, N. M., Collins, N., Zelazny, A. M., Prevots, D. R., Bending, D., Withers, D., Belkaid, Y., Segre, J. A. & Lionakis, M. S., 13 May 2022, (E-pub ahead of print) In: Cell Host & Microbe. 30, 7, p. 1020-1033.e6

Research output: Contribution to journal › Article › peer-review

Open Access

File

102 Downloads (Pure)

2020

The Diverse Roles of Monocytes in Cryptococcosis

Fu, M. S. & Drummond, R. A., 16 Jul 2020, In: Journal of Fungi. 6, 3, p. 1-14 111.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

211 Downloads (Pure)

2019

Candidalysin is required for neutrophil recruitment and virulence during systemic candida albicans infection

Swidergall, M., Khalaji, M., Solis, N. V., Moyes, D., Drummond, R., Hube, B., Lionakis, M. S., Murdoch, C., Filler, S. G. & Naglik, J. R., 1 Nov 2019, In: The Journal of Infectious Diseases. 220, 9, p. 1477–1488 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

25 Citations (Scopus)

200 Downloads (Pure)

CARD9⁺ Microglia Orchestrate Antifungal Immunity via IL-1β and CXCL1-mediated Neutrophil Recruitment

Drummond, R. A., Swamydas, M., Oikonomou, V., Zhai, B., Dambuza, I. M., Schaefer, B. C., Bohrer, A. C., Mayer-barber, K. D., Lira, S. A., Iwakura, Y., Filler, S. G., Brown, G. D., Hube, B., Naglik, J. R., Hohl, T. M. & Lionakis, M. S., May 2019, In: Nature Immunology. 20, 5, p. 559–570 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

54 Citations (Scopus)

184 Downloads (Pure)

The hidden cost of modern medical interventions: how medical advances have shaped the prevalence of human fungal disease

Clark, C. & Drummond, R., 4 Apr 2019, In: Pathogens. 8, 2, p. 1-11 11 p., 45.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

14 Citations (Scopus)

189 Downloads (Pure)

2018

Candidiasis of the central nervous system in neonates and children with primary immunodeficiencies

Drummond, R. A. & Lionakis, M. S., Jun 2018, In: Current Fungal Infection Reports. 12, 2, p. 92-97 6 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

GM-CSF therapy in human caspase recruitment domain–containing protein 9 deficiency

Drummond, R. A., Zahra, F. T., Natarajan, M., Swamydas, M., Hsu, A. P., Wheat, L. J., Gavino, C., Vinh, D. C., Holland, S. M., Mikelis, C. M. & Lionakis, M. S., Oct 2018, In: Journal of Allergy and Clinical Immunology. 142, 4, p. 1334-1338.e5 10 p.

Research output: Contribution to journal › Letter › peer-review

10 Citations (Scopus)

Human CARD9: a critical molecule of fungal immune surveillance

Drummond, R. A., Franco, L. M. & Lionakis, M. S., 6 Aug 2018, In: Frontiers in immunology. 9, 7 p., 1836.

Research output: Contribution to journal › Short survey › peer-review

Open Access

File

49 Citations (Scopus)

222 Downloads (Pure)

Microglia activation in Niemann-Pick disease, type C1 is amendable to therapeutic intervention

Cougnoux, A., Drummond, R. A., Collar, A. L., Iben, J. R., Salman, A., Westgarth, H., Wassif, C. A., Cawley, N. X., Farhat, N. Y., Ozato, K., Lionakis, M. S. & Porter, F. D., 15 Jun 2018, In: Human Molecular Genetics. 27, 12, p. 2076-2089 14 p.

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Organ-specific mechanisms linking innate and adaptive antifungal immunity

Drummond, R. A. & Lionakis, M. S., 1 Feb 2018, (E-pub ahead of print) In: Seminars in Cell and Developmental Biology.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

Kasper, L., König, A., Koenig, P. A., Gresnigt, M. S., Westman, J., Drummond, R. A., Lionakis, M. S., Groß, O., Ruland, J., Naglik, J. R. & Hube, B., 15 Dec 2018, In: Nature Communications. 9, 1, 4260.

Research output: Contribution to journal › Article › peer-review

Open Access

File

65 Citations (Scopus)

435 Downloads (Pure)

2017

An ocular commensal protects against corneal infection by driving an Interleukin-17 response from mucosal γδ T cells

St. Leger, A. J., Desai, J. V., Drummond, R. A., Kugadas, A., Almaghrabi, F., Silver, P., Raychaudhuri, K., Gadjeva, M., Iwakura, Y., Lionakis, M. S. & Caspi, R. R., 18 Jul 2017, In: Immunity. 47, 1, p. 148-158.e5 17 p.

Research output: Contribution to journal › Article › peer-review

107 Citations (Scopus)

Neuro-Immune Mechanisms of Anti-Cryptococcal Protection

Drummond, R. A., 25 Dec 2017, In: Journal of Fungi. 4, 1, 4.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

4 Citations (Scopus)

200 Downloads (Pure)

2016

CD4⁺ T-cell survival in the GI tract requires dectin-1 during fungal infection

Drummond, R. A., Dambuza, I. M., Vautier, S., Taylor, J. A., Reid, D. M., Bain, C. C., Underhill, D. M., Masopust, D., Kaplan, D. H. & Brown, G. D., 1 Mar 2016, In: Mucosal immunology. 9, 2, p. 492-502 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Citations (Scopus)

Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα₁₃/RhoA axis in B cells

O'Hayre, M., Inoue, A., Kufareva, I., Wang, Z., Mikelis, C. M., Drummond, R. A., Avino, S., Finkel, K., Kalim, K. W., Dipasquale, G., Guo, F., Aoki, J., Zheng, Y., Lionakis, M. S., Molinolo, A. A. & Gutkind, J. S., 21 Jul 2016, In: Oncogene. 35, 29, p. 3771-3780 10 p.

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Mechanistic insights into the role of C-type lectin receptor/CARD9 signaling in human antifungal immunity

Drummond, R. A. & Lionakis, M. S., 5 Apr 2016, In: Frontiers in cellular and infection microbiology. 6, APR, 11 p., 39.

Research output: Contribution to journal › Review article › peer-review

Open Access

68 Citations (Scopus)

MICL controls inflammation in rheumatoid arthritis

Redelinghuys, P., Whitehead, L., Augello, A., Drummond, R. A., Levesque, J. M., Vautier, S., Reid, D. M., Kerscher, B., Taylor, J. A., Nigrovic, P. A., Wright, J., Murray, G. I., Willment, J. A., Hocking, L. J., Fernandes, M. J. G., DeBari, C., Mcinnes, I. B. & Brown, G. D., 1 Jul 2016, In: Annals of the Rheumatic Diseases. 75, 7, p. 1386-1391 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Citations (Scopus)

Priming of the respiratory tract with immunobiotic Lactobacillus plantarum limits infection of alveolar macrophages with recombinant pneumonia virus of mice (rK2-PVM)

Dyer, K. D., Drummond, R. A., Rice, T. A., Percopo, C. M., Brenner, T. A., Barisas, D. A. G., Karpe, K. A., Moore, M. L. & Rosenberg, H. F., 1 Jan 2016, In: Journal of virology. 90, 2, p. 979-991 13 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2015

Candida albicans colonization and dissemination from the murine gastrointestinal tract: the influence of morphology and Th17 immunity

Vautier, S., Drummond, R. A., Chen, K., Murray, G. I., Kadosh, D., Brown, A. J. P., Gow, N. A. R., Maccallum, D. M., Kolls, J. K. & Brown, G. D., Apr 2015, In: Cellular Microbiology. 17, 4, p. 445-450 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Citations (Scopus)

Candida albicans morphology and dendritic cell subsets determine T helper cell differentiation

Kashem, S. W., Igyártó, B. Z., Gerami-Nejad, M., Kumamoto, Y., Mohammed, J., Jarrett, E., Drummond, R. A., Zurawski, S. M., Zurawski, G., Berman, J., Iwasaki, A., Brown, G. D. & Kaplan, D. H., 17 Feb 2015, In: Immunity. 42, 2, p. 356-366 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

120 Citations (Scopus)

CARD9-dependent neutrophil recruitment protects against fungal invasion of the central nervous system

Drummond, R. A., Collar, A. L., Swamydas, M., Rodriguez, C. A., Lim, J. K., Mendez, L. M., Fink, D. L., Hsu, A. P., Zhai, B., Karauzum, H., Mikelis, C. M., Rose, S. R., Ferre, E. M. N., Yockey, L., Lemberg, K., Kuehn, H. S., Rosenzweig, S. D., Lin, X., Chittiboina, P., Datta, S. K., & 6 othersBelhorn, T. H., Weimer, E. T., Hernandez, M. L., Hohl, T. M., Kuhns, D. B. & Lionakis, M. S., 17 Dec 2015, In: PLoS pathogens. 11, 12, 32 p., e1005293.

Research output: Contribution to journal › Article › peer-review

Open Access

100 Citations (Scopus)

Erratum: Microbial ligand costimulation drives neutrophilic steroid-refractory asthma (PLoS ONE (2015) 10:8 (e0134219))

Hadebe, S., Kirstein, F., Fierens, K., Chen, K., Drummond, R. A., Vautier, S., Sajaniemi, S., Murray, G., Williams, D. L., Redelinghuys, P., Reinhart, T. A., Fallert Junecko, B. A., Kolls, J. K., Lambrecht, B. N., Brombacher, F. & Brown, G. D., 8 Sept 2015, In: PLoS ONE. 10, 9, e0137945.

Research output: Contribution to journal › Comment/debate › peer-review

3 Citations (Scopus)

Innate defense against fungal pathogens

Drummond, R. A., Gaffen, S. L., Hise, A. G. & Brown, G. D., 1 Jun 2015, In: Cold Spring Harbor Perspectives in Medicine. 5, 6, 20 p., a019620.

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Microbial ligand costimulation drives neutrophilic steroid-refractory asthma

Hadebe, S., Kirstein, F., Fierens, K., Chen, K., Drummond, R. A., Vautier, S., Sajaniemi, S., Murray, G., Williams, D. L., Redelinghuys, P., Reinhart, T. A., Junecko, B. A. F., Kolls, J. K., Lambrecht, B. N., Brombacher, F., Brown, G. D. & Ryffel, B., 11 Aug 2015, In: PLoS ONE. 10, 8, 17 p., e0134219.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Citations (Scopus)

Pulmonary nontuberculous mycobacterial infection a multisystem, multigenic disease

Szymanski, E. P., Leung, J. M., Fowler, C. J., Haney, C., Hsu, A. P., Chen, F., Duggal, P., Oler, A. J., McCormack, R., Podack, E., Drummond, R. A., Lionakis, M. S., Browne, S. K., Prevots, D. R., Knowles, M., Cutting, G., Liu, X., Devine, S. E., Fraser, C. M., Tettelin, H., & 2 othersOlivier, K. N. & Holland, S. M., 1 Sept 2015, In: American Journal of Respiratory and Critical Care Medicine. 192, 5, p. 618-628 11 p.

Research output: Contribution to journal › Article › peer-review

79 Citations (Scopus)

The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity

Wilson, G. J., Marakalala, M. J., Hoving, J. C., van Laarhoven, A., Drummond, R. A., Kerscher, B., Keeton, R., van de Vosse, E., Ottenhoff, T. H. M., Plantinga, T. S., Alisjahbana, B., Govender, D., Besra, G. S., Netea, M. G., Reid, D. M., Willment, J. A., Jacobs, M., Yamasaki, S., van Crevel, R. & Brown, G. D., 11 Feb 2015, In: Cell Host & Microbe. 17, 2, p. 252-259 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

59 Citations (Scopus)

165 Downloads (Pure)

2014

Cutting edge: failure of antigen-specific CD4⁺ T cell recruitment to the kidney during systemic candidiasis

Drummond, R. A., Wallace, C., Reid, D. M., Way, S. S., Kaplan, D. H. & Brown, G. D., 1 Jan 2014, In: Journal of Immunology. 193, 11, p. 5381-5385 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

2013

Signalling C-type lectins in antimicrobial immunity

Drummond, R. A. & Brown, G. D., 25 Jul 2013, In: PLoS pathogens. 9, 7, 3 p., e1003417.

Research output: Contribution to journal › Article › peer-review

Open Access

82 Citations (Scopus)

2012

Dectin-1 is not required for controlling Candida albicans colonization of the gastrointestinal tract

Vautier, S., Drummond, R. A., Redelinghuys, P., Murray, G. I., MacCallum, D. M. & Brown, G. D., Dec 2012, In: Infection and Immunity. 80, 12, p. 4216-4222 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Citations (Scopus)

2011

The role of Dectin-1 in the host defence against fungal infections

Drummond, R. A. & Brown, G. D., Aug 2011, In: Current Opinion in Microbiology. 14, 4, p. 392-399 8 p.

Research output: Contribution to journal › Review article › peer-review

186 Citations (Scopus)

The role of Syk/CARD9 coupled C-type lectins in antifungal immunity

Drummond, R. A., Saijo, S., Iwakura, Y. & Brown, G. D., Feb 2011, In: European Journal of Immunology. 41, 2, p. 276-281 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

139 Citations (Scopus)

Rebecca Drummond

Research output

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