Centre for Liver and Gastrointestinal Research

Research output

Research output per year 2016 2021 2023 2024

• 7 Article
• 6 Comment/debate
• 5 Review article
• 2 Chapter
• 2 More
  • 1 Book
  • 1 Conference contribution

Research output per year

Research output per year

Search results

• 2024

  Implementation of a liver health check in people with type 2 diabetes

  Abeysekera, K. W. M., Valenti, L., Younossi, Z., Dillon, J. F., Allen, A. M., Nourredin, M., Rinella, M. E., Tacke, F., Francque, S., Ginès, P., Thiele, M., Newsome, P. N., Guha, I. N., Eslam, M., Schattenberg, J. M., Alqahtani, S. A., Arrese, M., Berzigotti, A., Holleboom, A. G., Caussy, C., & 8 othersCusi, K., Roden, M., Hagström, H., Wong, V. W. S., Mallet, V., Castera, L., Lazarus, J. V. & Tsochatzis, E. A., Jan 2024, In: The Lancet Gastroenterology and Hepatology. 9, 1, p. 83-91 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Liver Cirrhosis 100%
  • Type 2 Diabetes Mellitus 81%
  • Liver 55%
  • Health 52%
  • Non-alcoholic Fatty Liver Disease 38%

• Reply: NAFLD, MAFLD, or MASLD? Cut the Gordian knot with "Ludwig disease"

  Newsome, P., Rinella, M. E., Lazarus, J. V. & Terrault, N., Jan 2024, In: Hepatology. 79, 1, p. E5-E6 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Reply: 'From NAFLD to MASLD: Promise and pitfalls of a new definition'^†

  Rinella, M. E., Castro Narro, G. E., Krag, A., Terrault, N. & Newsome, P. N., Feb 2024, In: Hepatology. 79, 2, p. E16-E17 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
• 2023

  Bariatric–metabolic surgery versus lifestyle intervention in non-alcoholic steatohepatitis

  Mahgoub, S. & Newsome, P. N., 27 May 2023, In: The Lancet. 401, 10390, p. 1747-1749 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Cardiometabolic risk management: insights from a European Society of Cardiology Cardiovascular Round Table

  Cosentino, F., Verma, S., Ambery, P., Treppendahl, M. B., Van Eickels, M., Anker, S. D., Cecchini, M., Fioretto, P., Groop, P. H., Hess, D., Khunti, K., Lam, C. S. P., Richard-Lordereau, I., Lund, L. H., Mcgreavy, P., Newsome, P. N., Sattar, N., Solomon, S., Weidinger, F., Zannad, F., & 1 othersZeiher, A., 14 Oct 2023, In: European Heart Journal. 44, 39, p. 4141-4156 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Risk Management 100%
  • Cardiology 90%
  • Cardiovascular Diseases 66%
  • Obesity 63%
  • Chronic Renal Insufficiency 62%

• Efruxifermin in non-alcoholic steatohepatitis

  Mahgoub, S. & Newsome, P. N., Dec 2023, In: The Lancet Gastroenterology & Hepatology. 8, 12, p. 1058-1059 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Liver disease and cell therapy - advances made and remaining challenges

  Khan, S., Mahgoub, S., Fallatah, N., Lalor, P. F. & Newsome, P. N., 13 Apr 2023, In: Stem Cells. 41, 8

  Research output: Contribution to journal › Article › peer-review

  • Cell- and Tissue-Based Therapy 100%
  • Liver Diseases 88%
  • Clinical Studies 48%
  • End Stage Liver Disease 41%
  • Extracellular Vesicles 41%

• Semaglutide 2·4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial

  NN9931-4492 investigators, Jun 2023, In: The Lancet Gastroenterology & Hepatology. 8, 6, p. 511-522 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • semaglutide 100%
  • Fatty Liver 61%
  • Fibrosis 42%
  • Placebos 39%
  • Liver Cirrhosis 5%
  9 Downloads (Pure)

• Semaglutide in NASH-related cirrhosis: still a long way to go? – Authors' reply

  Loomba, R. & Newsome, P. N., Aug 2023, In: The Lancet Gastroenterology and Hepatology. 8, 8, p. 694-695 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• TGFβ₁ priming enhances CXCR3-mediated mesenchymal stromal cell engraftment to the liver and enhances anti-inflammatory efficacy

  Garg, A., Khan, S., Luu, N., Nicholas, D. J., Day, V., King, A. L., Fear, J., Lalor, P. F. & Newsome, P. N., Mar 2023, In: Journal of Cellular and Molecular Medicine. 27, 6, p. 864-878 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mesenchymal Stem Cells 100%
  • Anti-Inflammatory Agents 82%
  • Liver 57%
  • Wounds and Injuries 21%
  • Endothelium 19%
  36 Downloads (Pure)
• 2022

  Common mechanisms in pediatric acute liver failure

  Mann, J. P., Lenz, D., Stamataki, Z. & Kelly, D., 7 Dec 2022, (E-pub ahead of print) In: Trends in Molecular Medicine. 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Acute Liver Failure 100%
  • Pediatrics 54%
  • Loss of Function Mutation 32%
  • Regulatory T-Lymphocytes 28%
  • Hepatitis 26%
  56 Downloads (Pure)
• 2021

  Ex situ Normothermic Split Liver Machine Perfusion: Protocol for Robust Comparative Controls in Liver Function Assessment Suitable for Evaluation of Novel Therapeutic Interventions in the Pre-clinical Setting

  Attard, J. A., Osei-Bordom, D-C., Boteon, Y., Wallace, L., Ronca, V., Reynolds, G., Perera, M. T. P. R., Oo, Y. H., Mergental, H., Mirza, D. F. & Afford, S. C., 17 Feb 2021, In: Frontiers in Surgery. 8, 627332.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Perfusion 100%
  • Liver 68%
  • Hepatic Veins 39%
  • Hepatic Artery 37%
  • Portal Vein 33%
  1 Citation (Scopus)

  218 Downloads (Pure)

• Liver Transplantation: Clinical Assessment and Management. Second Edition

  Neuberger, J. (ed.), Ferguson, J. (ed.), Newsome, P. N. (ed.) & Lucey, M. R. (ed.), 12 Mar 2021, 2 ed. Wiley-VCH Verlag. 559 p.

  Research output: Book/Report › Book

  • Liver Transplantation 100%
  • Gastroenterology 37%
  • Transplant Recipients 23%
  • Liver Diseases 21%
  • Gastroenterologists 20%

• NAFLD and NASH in the Patient after Liver Transplantation

  Horn, P. & Newsome, P. N., 19 Apr 2021, Liver Transplantation: Clinical Assessment and Management. Second Edition. Neuberger, J., Ferguson, J., Newsome, P. N. & Lucey, M. R. (eds.). 2 ed. Wiley-VCH Verlag, p. 438-444 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Non-alcoholic Fatty Liver Disease 100%
  • Fatty Liver 99%
  • Liver Transplantation 84%
  • Transplants 29%
  • Liver Diseases 26%

• Non-alcoholic Fatty Liver Disease as an Indication for Liver Transplantation

  Horn, P. & Newsome, P. N., 19 Apr 2021, Liver Transplantation: Clinical Assessment and Management: Second edition. Neuberger, J., Ferguson, J., Newsome, P. N. & Lucey, M. R. (eds.). 2 ed. Wiley-VCH Verlag, p. 104-108 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Non-alcoholic Fatty Liver Disease 100%
  • Liver Transplantation 84%
  • End Stage Liver Disease 36%
  • Obesity 32%
  • Metabolic Syndrome 28%

• Sarcopenia in inflammatory bowel disease: a narrative overview

  Dhaliwal, A., Quinlan, J. I., Overthrow, K., Greig, C., Lord, J. M., Armstrong, M. J. & Cooper, S. C., 17 Feb 2021, In: Nutrients. 13, 2, 656.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • sarcopenia 100%
  • inflammatory bowel disease 82%
  • Sarcopenia 68%
  • Inflammatory Bowel Diseases 51%
  • ulcerative colitis 14%
  2 Citations (Scopus)

  211 Downloads (Pure)

• Scavenger Receptors: Novel Roles in the Pathogenesis of Liver Inflammation and Cancer

  Patten, D. A., Wilkinson, A. L., O'Keeffe, A. & Shetty, S., 22 Sept 2021, (E-pub ahead of print) In: Seminars in Liver Disease. 42, 1, p. 61-76 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Scavenger Receptors 100%
  • Liver Neoplasms 76%
  • Inflammation 45%
  • Liver 39%
  • Homeostasis 22%
  30 Downloads (Pure)

• The human liver microenvironment shapes the homing and function of CD4+ T-cell populations

  Wiggins, B. G., Pallett, L. J., Li, X., Davies, S. P., Amin, O. E., Gill, U. S., Kucykowicz, S., Patel, A. M., Aliazis, K., Liu, Y. S., Reynolds, G. M., Davidson, B. R., Gander, A., Luong, T. V., Hirschfield, G. M., Kennedy, P. T. F., Huang, Y., Maini, M. K. & Stamataki, Z., 21 Sept 2021, (E-pub ahead of print) In: Gut.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • T-Lymphocytes 100%
  • Liver 83%
  • Population 63%
  • HLA Antigens 49%
  • Allografts 42%
  47 Downloads (Pure)
• 2020

  Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics (Nature Communications, (2020), 11, 1, (467), 10.1038/s41467-020-14309-w)

  Ast, J., Arvaniti, A., Fine, N. H. F., Nasteska, D., Ashford, F. B., Stamataki, Z., Koszegi, Z., Bacon, A., Jones, B. J., Lucey, M. A., Sasaki, S., Brierley, D. I., Hastoy, B., Tomas, A., D’Agostino, G., Reimann, F., Lynn, F. C., Reissaus, C. A., Linnemann, A. K., D’Este, E., & 6 othersCalebiro, D., Trapp, S., Johnsson, K., Podewin, T., Broichhagen, J. & Hodson, D. J., 1 Dec 2020, In: Nature Communications. 11, 1, 5160.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • ethics 100%
  • Glucagon-Like Peptide 1 91%
  • Glucagon-Like Peptide-1 Receptor 74%
  • Human Embryonic Stem Cells 69%
  • peptides 63%
  2 Citations (Scopus)

• Cell Therapy for Liver Disease: From Promise to Reality

  Khan, S., Khan, R. S. & Newsome, P. N., 1 Nov 2020, In: Seminars in Liver Disease. 40, 4, p. 411-425 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell- and Tissue-Based Therapy 100%
  • Liver Diseases 88%
  • Macrophages 29%
  • Hospital Costs 24%
  • Allogeneic Cells 22%
  1 Citation (Scopus)

• Immunological mechanisms underpinning faecal microbiota transplantation for the treatment of inflammatory bowel disease

  Quraishi, M. N., Shaheen, W., Oo, Y. H. & Iqbal, T., Jan 2020, In: Clinical and Experimental Immunology. 199, 1, p. 24-38 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Fecal Microbiota Transplantation 100%
  • Inflammatory Bowel Diseases 65%
  • Dysbiosis 43%
  • Gastrointestinal Microbiome 34%
  • Inflammation 30%
  15 Citations (Scopus)
• 2016

  Development of a multi-modal optical imaging system

  Taylor, S. L., Newsome, P. N. & Dehghani, H., 18 Apr 2016, Optical Tomography and Spectroscopy, OTS 2016. Optica Publishing Group (formerly OSA), p. 3 1 p. (Optics InfoBase Conference Papers).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Bioluminescence 100%
  • Optical tomography 80%
  • Imaging systems 62%
  • Tomography 56%
  • Tissue 50%