Alan Jones

Dr, Dr.

Accepting PhD Students

PhD projects

The Jones research group has been funded by BISCA, the Wellcome Trust (UK), CRISM Therapeutics/Imphatec Ltd (Industry UK/Ireland), Medical Research Council (UK), the Royal Society of Chemistry (UK), CAPES (Brazil), Bolashak Foundation (Kazakhstan), LPDP (Indonesia), EJSP (Saudi Arabia), UNESP (Brazil), Erasmus+ mobility programme (EU), British Council (UK Govt), Science without Borders (Brazil), the Government of Botswana (Botswana), the Royal Society (London), King Khalid University (Saudi Arabia), and University of Birmingham amongst others. He was awarded alongside his collaborators (Wilkinson and Alexander) the Healthcare Science Excellence Prize in 2016. During his career he has published over 75+ research papers, 3 patents, and 2 book chapters.

The main theme of the multi-disciplinary research in the group is the development of underpinning science that pushes the boundaries of the chemical sciences within drug discovery. Prominent topics of research include:
1) electrosynthesis of drug metabolites including the late-stage modification of small molecules and peptides;
2) novel synthetic routes to sulfated bioactive molecules and peptides;
3) drug discovery projects including the small molecule allosteric inhibition of EAAT1 for T-ALL, design of novel EGFR/HER2 inhibitors for oncology, AI in drug development, and a glycomimetic platform for HGF-cMET modulation for cardiovascular indications; and 4) polypharmacology as a determinant of adverse drug reactions and drug toxicity in real-world settings.

PhD student enquires are welcome:

[1] Polypharmacology and Side Effects of Drugs, see: https://www.findaphd.com/phds/project/pharmacovigilance-and-polypharmacology-identification-of-differential-side-effects-within-drug-classes-and-links-to-their-unique-modes-of-action/?p171337

[2] Electrochemical synthesis of Drug Metabolites, see: https://www.findaphd.com/phds/project/drug-metabolism-prediction-detection-and-isolation/?p171338

[3] Targeting amino-acid transporters for treatment of cancer and neurological disorders (co-I with Dr Felix Chan), see: https://www.findaphd.com/phds/project/targeting-amino-acid-transporters-for-treatment-of-cancer-and-neurological-disorders/?p181764

20092024

Research activity per year

Personal profile

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy

Education/Academic qualification

Doctor of Philosophy, University of St Andrews

Sept 2005Feb 2009

Award Date: 25 Jun 2009

Bachelor of Science, University of Aberdeen

Sept 2001Jul 2005

Award Date: 5 Jul 2005

Keywords

  • QD Chemistry
  • medicinal chemistry
  • drug discovery
  • synthetic chemistry
  • electrochemistry

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