Simultaneous diffuse optical and bioluminescence tomography to improve source localization

Alexander Bentley, Xiangkun Xu, Zijian Deng, Jonathan E. Rowe, Ken Kang Hsin Wang, Hamid Dehghani*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A novel algorithm to simultaneously recover bioluminescence source location and optical parameters is developed. In-vivo studies show 30% improvement in localization error while also providing local total hemoglobin concentration.

Original languageEnglish
Title of host publicationDiffuse Optical Spectroscopy and Imaging VIII
EditorsDavide Contini, Yoko Hoshi, Thomas D. O'Sullivan
PublisherSPIE
ISBN (Electronic)9781510647060
DOIs
Publication statusPublished - 9 Dec 2021
EventDiffuse Optical Spectroscopy and Imaging VIII 2021 - Virtual, Online, Germany
Duration: 20 Jun 202124 Jun 2021

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11920
ISSN (Print)1605-7422

Conference

ConferenceDiffuse Optical Spectroscopy and Imaging VIII 2021
Country/TerritoryGermany
CityVirtual, Online
Period20/06/2124/06/21

Bibliographical note

Funding Information:
The author would like to acknowledge financial support from EPSRC through a studentship from the Physical Sciences for Health Centre for Doctoral Training (EP/L016346/1) and NIH R01CA240811, R37CA230341, R21CA223403, and CPRIT RR200042.

Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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