Simultaneous diffuse optical and bioluminescence tomography to improve source localization

Alexander Bentley; Xiangkun Xu; Zijian Deng; Jonathan E. Rowe; Ken Kang Hsin Wang; Hamid Dehghani

doi:10.1117/12.2615347

Simultaneous diffuse optical and bioluminescence tomography to improve source localization

Alexander Bentley, Xiangkun Xu, Zijian Deng, Jonathan E. Rowe, Ken Kang Hsin Wang, Hamid Dehghani^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A novel algorithm to simultaneously recover bioluminescence source location and optical parameters is developed. In-vivo studies show 30% improvement in localization error while also providing local total hemoglobin concentration.

Original language	English
Title of host publication	Diffuse Optical Spectroscopy and Imaging VIII
Editors	Davide Contini, Yoko Hoshi, Thomas D. O'Sullivan
Publisher	SPIE
ISBN (Electronic)	9781510647060
DOIs	https://doi.org/10.1117/12.2615347
Publication status	Published - 9 Dec 2021
Event	Diffuse Optical Spectroscopy and Imaging VIII 2021 - Virtual, Online, Germany Duration: 20 Jun 2021 → 24 Jun 2021

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	11920
ISSN (Print)	1605-7422

Conference

Conference	Diffuse Optical Spectroscopy and Imaging VIII 2021
Country/Territory	Germany
City	Virtual, Online
Period	20/06/21 → 24/06/21

Bibliographical note

Funding Information:
The author would like to acknowledge financial support from EPSRC through a studentship from the Physical Sciences for Health Centre for Doctoral Training (EP/L016346/1) and NIH R01CA240811, R37CA230341, R21CA223403, and CPRIT RR200042.

Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

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10.1117/12.2615347Licence: None: All rights reserved

Cite this

Bentley, A., Xu, X., Deng, Z., Rowe, J. E., Wang, K. K. H., & Dehghani, H. (2021). Simultaneous diffuse optical and bioluminescence tomography to improve source localization. In D. Contini, Y. Hoshi, & T. D. O'Sullivan (Eds.), Diffuse Optical Spectroscopy and Imaging VIII Article 1192016 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11920). SPIE. https://doi.org/10.1117/12.2615347

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title = "Simultaneous diffuse optical and bioluminescence tomography to improve source localization",

abstract = "A novel algorithm to simultaneously recover bioluminescence source location and optical parameters is developed. In-vivo studies show 30% improvement in localization error while also providing local total hemoglobin concentration.",

author = "Alexander Bentley and Xiangkun Xu and Zijian Deng and Rowe, {Jonathan E.} and Wang, {Ken Kang Hsin} and Hamid Dehghani",

note = "Funding Information: The author would like to acknowledge financial support from EPSRC through a studentship from the Physical Sciences for Health Centre for Doctoral Training (EP/L016346/1) and NIH R01CA240811, R37CA230341, R21CA223403, and CPRIT RR200042. Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Diffuse Optical Spectroscopy and Imaging VIII 2021 ; Conference date: 20-06-2021 Through 24-06-2021",

year = "2021",

month = dec,

day = "9",

doi = "10.1117/12.2615347",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

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Bentley, A, Xu, X, Deng, Z, Rowe, JE, Wang, KKH & Dehghani, H 2021, Simultaneous diffuse optical and bioluminescence tomography to improve source localization. in D Contini, Y Hoshi & TD O'Sullivan (eds), Diffuse Optical Spectroscopy and Imaging VIII., 1192016, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 11920, SPIE, Diffuse Optical Spectroscopy and Imaging VIII 2021, Virtual, Online, Germany, 20/06/21. https://doi.org/10.1117/12.2615347

Simultaneous diffuse optical and bioluminescence tomography to improve source localization. / Bentley, Alexander; Xu, Xiangkun; Deng, Zijian et al.
Diffuse Optical Spectroscopy and Imaging VIII. ed. / Davide Contini; Yoko Hoshi; Thomas D. O'Sullivan. SPIE, 2021. 1192016 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11920).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Simultaneous diffuse optical and bioluminescence tomography to improve source localization

AU - Bentley, Alexander

AU - Xu, Xiangkun

AU - Deng, Zijian

AU - Rowe, Jonathan E.

AU - Wang, Ken Kang Hsin

AU - Dehghani, Hamid

N1 - Funding Information: The author would like to acknowledge financial support from EPSRC through a studentship from the Physical Sciences for Health Centre for Doctoral Training (EP/L016346/1) and NIH R01CA240811, R37CA230341, R21CA223403, and CPRIT RR200042. Publisher Copyright: © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

PY - 2021/12/9

Y1 - 2021/12/9

N2 - A novel algorithm to simultaneously recover bioluminescence source location and optical parameters is developed. In-vivo studies show 30% improvement in localization error while also providing local total hemoglobin concentration.

AB - A novel algorithm to simultaneously recover bioluminescence source location and optical parameters is developed. In-vivo studies show 30% improvement in localization error while also providing local total hemoglobin concentration.

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DO - 10.1117/12.2615347

M3 - Conference contribution

AN - SCOPUS:85122861150

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Diffuse Optical Spectroscopy and Imaging VIII

A2 - Contini, Davide

A2 - Hoshi, Yoko

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PB - SPIE

T2 - Diffuse Optical Spectroscopy and Imaging VIII 2021

Y2 - 20 June 2021 through 24 June 2021

ER -

Simultaneous diffuse optical and bioluminescence tomography to improve source localization

Abstract

Publication series

Conference

Bibliographical note

ASJC Scopus subject areas

Access to Document

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Cite this