Pathogenesis of non-alcoholic fatty liver disease.

Joanna Dowman, Jeremy Tomlinson, Philip Newsome

Research output: Contribution to journalArticlepeer-review

415 Citations (Scopus)
273 Downloads (Pure)


Non-alcoholic fatty liver disease (NAFLD) represents a spectrum of disease ranging from hepatocellular steatosis through steatohepatitis to fibrosis and irreversible cirrhosis. The prevalence of NAFLD has risen rapidly in parallel with the dramatic rise in obesity and diabetes, and is rapidly becoming the most common cause of liver disease in Western countries. Indeed, NAFLD is now recognized to be the aetiology in many cases previously labelled as cryptogenic cirrhosis.
Original languageEnglish
Pages (from-to)71-83
Issue number2
Early online date13 Nov 2009
Publication statusPublished - 1 Feb 2010

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