Near-infrared optical tomography: Endoscopic imaging approach

Daqing Piao; Hao Xie; Cameron Musgrove; Charles F. Bunting; Weili Zhang; Guolong Zhang; Ellen B. Domnick-Davidsion; Kenneth E. Bartels; G. Reed Holyoak; Sreenivas N. Vemulapalli; Hamid Dehghani; Brian W. Pogue

doi:10.1117/12.695217

Near-infrared optical tomography: Endoscopic imaging approach

Daqing Piao^*, Hao Xie, Cameron Musgrove, Charles F. Bunting, Weili Zhang, Guolong Zhang, Ellen B. Domnick-Davidsion, Kenneth E. Bartels, G. Reed Holyoak, Sreenivas N. Vemulapalli, Hamid Dehghani, Brian W. Pogue

^*Corresponding author for this work

Computer Science

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Near-infrared optical tomography is an interesting technique of imaging with high blood-based contrast. Unfortunately non-invasive NIR tomographic imaging has been restricted to specific organs like breast that can be transilluminated externally. In this paper, we demonstrate that near-infrared (NIR) optical tomography can be employed at the endoscopescale, and implemented at a rapid sampling speed that allows translation to in vivo use. A spread-spectral-encoding technique based on a broadband light source is combined with light delivery by linear-to-circular fiber bundle, to provide endoscopic probing of multiple source/detector fibers for tomographic imaging as well as parallel sampling of all source-detector pairs for rapid data acquisition. Endoscopic NIR tomography is demonstrated by use of a 12mm diameter probe housing 8 sources and 8 detectors at 8 Hz frame rate. Transrectal NIR optical tomography by use of tissue specimen is also presented. This novel approach provides the key feasibility studies to allow this blood-based contrast imaging technology to be tried in cancer detection of internal organs via endoscopic interrogation.

Original language	English
Title of host publication	Multimodal Biomedical Imaging II
DOIs	https://doi.org/10.1117/12.695217
Publication status	Published - 2007
Event	Multimodal Biomedical Imaging II - San Jose, CA, United States Duration: 20 Jan 2007 → 23 Jan 2007

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	6431
ISSN (Print)	1605-7422

Conference

Conference	Multimodal Biomedical Imaging II
Country/Territory	United States
City	San Jose, CA
Period	20/01/07 → 23/01/07

Keywords

Endoscopic
Near-infrared optical tomography
Reconstruction
Trans-rectal

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1117/12.695217

Cite this

Piao, D., Xie, H., Musgrove, C., Bunting, C. F., Zhang, W., Zhang, G., Domnick-Davidsion, E. B., Bartels, K. E., Holyoak, G. R., Vemulapalli, S. N., Dehghani, H., & Pogue, B. W. (2007). Near-infrared optical tomography: Endoscopic imaging approach. In Multimodal Biomedical Imaging II Article 643103 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6431). https://doi.org/10.1117/12.695217

@inproceedings{c78f864bf02a47ad8423c4e4292a5d4e,

title = "Near-infrared optical tomography: Endoscopic imaging approach",

abstract = "Near-infrared optical tomography is an interesting technique of imaging with high blood-based contrast. Unfortunately non-invasive NIR tomographic imaging has been restricted to specific organs like breast that can be transilluminated externally. In this paper, we demonstrate that near-infrared (NIR) optical tomography can be employed at the endoscopescale, and implemented at a rapid sampling speed that allows translation to in vivo use. A spread-spectral-encoding technique based on a broadband light source is combined with light delivery by linear-to-circular fiber bundle, to provide endoscopic probing of multiple source/detector fibers for tomographic imaging as well as parallel sampling of all source-detector pairs for rapid data acquisition. Endoscopic NIR tomography is demonstrated by use of a 12mm diameter probe housing 8 sources and 8 detectors at 8 Hz frame rate. Transrectal NIR optical tomography by use of tissue specimen is also presented. This novel approach provides the key feasibility studies to allow this blood-based contrast imaging technology to be tried in cancer detection of internal organs via endoscopic interrogation.",

keywords = "Endoscopic, Near-infrared optical tomography, Reconstruction, Trans-rectal",

author = "Daqing Piao and Hao Xie and Cameron Musgrove and Bunting, {Charles F.} and Weili Zhang and Guolong Zhang and Domnick-Davidsion, {Ellen B.} and Bartels, {Kenneth E.} and Holyoak, {G. Reed} and Vemulapalli, {Sreenivas N.} and Hamid Dehghani and Pogue, {Brian W.}",

year = "2007",

doi = "10.1117/12.695217",

language = "English",

isbn = "0819465445",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

booktitle = "Multimodal Biomedical Imaging II",

note = "Multimodal Biomedical Imaging II ; Conference date: 20-01-2007 Through 23-01-2007",

}

Piao, D, Xie, H, Musgrove, C, Bunting, CF, Zhang, W, Zhang, G, Domnick-Davidsion, EB, Bartels, KE, Holyoak, GR, Vemulapalli, SN, Dehghani, H & Pogue, BW 2007, Near-infrared optical tomography: Endoscopic imaging approach. in Multimodal Biomedical Imaging II., 643103, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 6431, Multimodal Biomedical Imaging II, San Jose, CA, United States, 20/01/07. https://doi.org/10.1117/12.695217

TY - GEN

T1 - Near-infrared optical tomography

T2 - Multimodal Biomedical Imaging II

AU - Piao, Daqing

AU - Xie, Hao

AU - Musgrove, Cameron

AU - Bunting, Charles F.

AU - Zhang, Weili

AU - Zhang, Guolong

AU - Domnick-Davidsion, Ellen B.

AU - Bartels, Kenneth E.

AU - Holyoak, G. Reed

AU - Vemulapalli, Sreenivas N.

AU - Dehghani, Hamid

AU - Pogue, Brian W.

PY - 2007

Y1 - 2007

N2 - Near-infrared optical tomography is an interesting technique of imaging with high blood-based contrast. Unfortunately non-invasive NIR tomographic imaging has been restricted to specific organs like breast that can be transilluminated externally. In this paper, we demonstrate that near-infrared (NIR) optical tomography can be employed at the endoscopescale, and implemented at a rapid sampling speed that allows translation to in vivo use. A spread-spectral-encoding technique based on a broadband light source is combined with light delivery by linear-to-circular fiber bundle, to provide endoscopic probing of multiple source/detector fibers for tomographic imaging as well as parallel sampling of all source-detector pairs for rapid data acquisition. Endoscopic NIR tomography is demonstrated by use of a 12mm diameter probe housing 8 sources and 8 detectors at 8 Hz frame rate. Transrectal NIR optical tomography by use of tissue specimen is also presented. This novel approach provides the key feasibility studies to allow this blood-based contrast imaging technology to be tried in cancer detection of internal organs via endoscopic interrogation.

AB - Near-infrared optical tomography is an interesting technique of imaging with high blood-based contrast. Unfortunately non-invasive NIR tomographic imaging has been restricted to specific organs like breast that can be transilluminated externally. In this paper, we demonstrate that near-infrared (NIR) optical tomography can be employed at the endoscopescale, and implemented at a rapid sampling speed that allows translation to in vivo use. A spread-spectral-encoding technique based on a broadband light source is combined with light delivery by linear-to-circular fiber bundle, to provide endoscopic probing of multiple source/detector fibers for tomographic imaging as well as parallel sampling of all source-detector pairs for rapid data acquisition. Endoscopic NIR tomography is demonstrated by use of a 12mm diameter probe housing 8 sources and 8 detectors at 8 Hz frame rate. Transrectal NIR optical tomography by use of tissue specimen is also presented. This novel approach provides the key feasibility studies to allow this blood-based contrast imaging technology to be tried in cancer detection of internal organs via endoscopic interrogation.

KW - Endoscopic

KW - Near-infrared optical tomography

KW - Reconstruction

KW - Trans-rectal

UR - http://www.scopus.com/inward/record.url?scp=34247344481&partnerID=8YFLogxK

U2 - 10.1117/12.695217

DO - 10.1117/12.695217

M3 - Conference contribution

AN - SCOPUS:34247344481

SN - 0819465445

SN - 9780819465443

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Multimodal Biomedical Imaging II

Y2 - 20 January 2007 through 23 January 2007

ER -

Near-infrared optical tomography: Endoscopic imaging approach

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Fingerprint

Cite this