@inproceedings{c78f864bf02a47ad8423c4e4292a5d4e,
title = "Near-infrared optical tomography: Endoscopic imaging approach",
abstract = "Near-infrared optical tomography is an interesting technique of imaging with high blood-based contrast. Unfortunately non-invasive NIR tomographic imaging has been restricted to specific organs like breast that can be transilluminated externally. In this paper, we demonstrate that near-infrared (NIR) optical tomography can be employed at the endoscopescale, and implemented at a rapid sampling speed that allows translation to in vivo use. A spread-spectral-encoding technique based on a broadband light source is combined with light delivery by linear-to-circular fiber bundle, to provide endoscopic probing of multiple source/detector fibers for tomographic imaging as well as parallel sampling of all source-detector pairs for rapid data acquisition. Endoscopic NIR tomography is demonstrated by use of a 12mm diameter probe housing 8 sources and 8 detectors at 8 Hz frame rate. Transrectal NIR optical tomography by use of tissue specimen is also presented. This novel approach provides the key feasibility studies to allow this blood-based contrast imaging technology to be tried in cancer detection of internal organs via endoscopic interrogation.",
keywords = "Endoscopic, Near-infrared optical tomography, Reconstruction, Trans-rectal",
author = "Daqing Piao and Hao Xie and Cameron Musgrove and Bunting, {Charles F.} and Weili Zhang and Guolong Zhang and Domnick-Davidsion, {Ellen B.} and Bartels, {Kenneth E.} and Holyoak, {G. Reed} and Vemulapalli, {Sreenivas N.} and Hamid Dehghani and Pogue, {Brian W.}",
year = "2007",
doi = "10.1117/12.695217",
language = "English",
isbn = "0819465445",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Multimodal Biomedical Imaging II",
note = "Multimodal Biomedical Imaging II ; Conference date: 20-01-2007 Through 23-01-2007",
}