Molecular basis of haematological disease caused by inherited or acquired RUNX1 mutations

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• Finished

  Finding therapeutic targets in FLT3-ITD AML using a systems biology approach

  Cockerill, P. & Bonifer, C.

  Medical Research Council

  1/09/19 → 31/12/23

  Project: Research Councils

  • Gene Regulatory Networks 100%
  • Acute Myeloid Leukemia 95%
  • Chromatin 62%
  • Transcription Factors 56%
  • Mutation 42%

• Mechanistic insights into aberrant transcriptional programming in acute myeloid leukaemia

  Bonifer, C. & Cockerill, P.

  BLOODWISE

  1/07/15 → 31/12/21

  Project: Research

  • Acute Myeloid Leukemia 100%
  • Mutation 88%
  • Oncogenic 73%
  • Wilms Tumor 62%
  • Transcription Factors 62%