Incidence of cancers following orthotopic liver transplantation in a single centre: comparison with national cancer incidence rates for England and Wales

Ye Htun Oo; Bridget Gunson; Robert Lancashire; Kar Cheng; James Neuberger

doi:10.1097/01.TP.0000173775.16579.18

Incidence of cancers following orthotopic liver transplantation in a single centre: comparison with national cancer incidence rates for England and Wales

Ye Htun Oo, Bridget Gunson, Robert Lancashire, Kar Cheng, James Neuberger

Research output: Contribution to journal › Article › peer-review

78 Citations (Scopus)

Abstract

Background. The incidence of de novo cancers is increased in liver allograft recipients but there are few data assessing the extent of the increased risk compared with a matched population. Methods. A retrospective study of 1,778 adults transplanted between January 1982 and March 2004, followed for a median of 65 months. The observed cancer incidence was compared with age-, sex-, and calendar year-matched expected cancer rates in England and Wales population. Results. In all, 141 (7.9%) developed a new cancer. There was an increase in the incidence of all tumors compared with that expected (Standardized Incidence Ratio (SIR) 207, 95% Cl 174-244, P

Original language	English
Pages (from-to)	759-764
Number of pages	6
Journal	Transplantation
Volume	80
Issue number	6
DOIs	https://doi.org/10.1097/01.TP.0000173775.16579.18
Publication status	Published - 27 Sept 2005

Keywords

orthotopic liver transplantation
de novo cancer
standardized incidence ratio

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Incidence of cancers following orthotopic liver transplantation in a single centre: comparison with national cancer incidence rates for England and Wales",

abstract = "Background. The incidence of de novo cancers is increased in liver allograft recipients but there are few data assessing the extent of the increased risk compared with a matched population. Methods. A retrospective study of 1,778 adults transplanted between January 1982 and March 2004, followed for a median of 65 months. The observed cancer incidence was compared with age-, sex-, and calendar year-matched expected cancer rates in England and Wales population. Results. In all, 141 (7.9%) developed a new cancer. There was an increase in the incidence of all tumors compared with that expected (Standardized Incidence Ratio (SIR) 207, 95% Cl 174-244, P",

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T1 - Incidence of cancers following orthotopic liver transplantation in a single centre: comparison with national cancer incidence rates for England and Wales

AU - Oo, Ye Htun

AU - Gunson, Bridget

AU - Lancashire, Robert

AU - Cheng, Kar

AU - Neuberger, James

PY - 2005/9/27

Y1 - 2005/9/27

N2 - Background. The incidence of de novo cancers is increased in liver allograft recipients but there are few data assessing the extent of the increased risk compared with a matched population. Methods. A retrospective study of 1,778 adults transplanted between January 1982 and March 2004, followed for a median of 65 months. The observed cancer incidence was compared with age-, sex-, and calendar year-matched expected cancer rates in England and Wales population. Results. In all, 141 (7.9%) developed a new cancer. There was an increase in the incidence of all tumors compared with that expected (Standardized Incidence Ratio (SIR) 207, 95% Cl 174-244, P

AB - Background. The incidence of de novo cancers is increased in liver allograft recipients but there are few data assessing the extent of the increased risk compared with a matched population. Methods. A retrospective study of 1,778 adults transplanted between January 1982 and March 2004, followed for a median of 65 months. The observed cancer incidence was compared with age-, sex-, and calendar year-matched expected cancer rates in England and Wales population. Results. In all, 141 (7.9%) developed a new cancer. There was an increase in the incidence of all tumors compared with that expected (Standardized Incidence Ratio (SIR) 207, 95% Cl 174-244, P

KW - orthotopic liver transplantation

KW - de novo cancer

KW - standardized incidence ratio

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JO - Transplantation

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ER -

Incidence of cancers following orthotopic liver transplantation in a single centre: comparison with national cancer incidence rates for England and Wales

Abstract

Keywords

UN SDGs

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