High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy

Robin Dale; Thomas D. O’Sullivan; Scott Howard; Chris Campbell; Felipe Orihuela-Espina; Hamid Dehghani

doi:10.1117/12.2651676

High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy

Robin Dale^*, Thomas D. O’Sullivan, Scott Howard, Chris Campbell, Felipe Orihuela-Espina, Hamid Dehghani

^*Corresponding author for this work

Computer Science

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Abstract

Frequency domain (FD) diffuse optical spectroscopy (DOS) can be used to recover absolute optical properties of biological tissue, providing valuable clinical feedback, including in diagnosis and monitoring of breast tumours. In this study, tomographic (3D) and topographic (2D) techniques for spatially-varying optical parameter recovery are presented, based on a multi-distance, handheld DOS probe. Processing pipelines and reconstruction quality are discussed and quantitatively compared, demonstrating the trade-offs between depth sensitivity, optical contrast, and computational speed. Together, the two techniques provide both depth sensitive real-time feedback, and high-resolution 3D reconstruction from a single set of measurements, enabling faster and more accurate clinical feedback.

Original language	English
Title of host publication	Optical Tomography and Spectroscopy of Tissue XV
Editors	Sergio Fantini, Paola Taroni
Publisher	SPIE
ISBN (Electronic)	9781510658585
ISBN (Print)	9781510658578
DOIs	https://doi.org/10.1117/12.2651676
Publication status	Published - 7 Mar 2023
Event	Optical Tomography and Spectroscopy of Tissue XV 2023 - San Francisco, United States Duration: 30 Jan 2023 → 1 Feb 2023

Publication series

Name	Proceedings of SPIE. Progress in biomedical optics and imaging
Volume	12376
ISSN (Print)	1605-7422
ISSN (Electronic)	2410-9045

Conference

Conference	Optical Tomography and Spectroscopy of Tissue XV 2023
Country/Territory	United States
City	San Francisco
Period	30/01/23 → 1/02/23

Bibliographical note

Funding Information:
Research reported in this publication was supported by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) of the National Institutes of Health (NIH) Award Number R01EB029595

Publisher Copyright:
© 2023 SPIE.

Keywords

diffuse optical spectroscopy
diffuse optical tomography
topography

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2651676

DaleR2023hIGH
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Cite this

Dale, R., O’Sullivan, T. D., Howard, S., Campbell, C., Orihuela-Espina, F., & Dehghani, H. (2023). High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy. In S. Fantini, & P. Taroni (Eds.), Optical Tomography and Spectroscopy of Tissue XV Article 1237606 (Proceedings of SPIE. Progress in biomedical optics and imaging; Vol. 12376). SPIE. https://doi.org/10.1117/12.2651676

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abstract = "Frequency domain (FD) diffuse optical spectroscopy (DOS) can be used to recover absolute optical properties of biological tissue, providing valuable clinical feedback, including in diagnosis and monitoring of breast tumours. In this study, tomographic (3D) and topographic (2D) techniques for spatially-varying optical parameter recovery are presented, based on a multi-distance, handheld DOS probe. Processing pipelines and reconstruction quality are discussed and quantitatively compared, demonstrating the trade-offs between depth sensitivity, optical contrast, and computational speed. Together, the two techniques provide both depth sensitive real-time feedback, and high-resolution 3D reconstruction from a single set of measurements, enabling faster and more accurate clinical feedback.",

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Dale, R, O’Sullivan, TD, Howard, S, Campbell, C, Orihuela-Espina, F & Dehghani, H 2023, High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy. in S Fantini & P Taroni (eds), Optical Tomography and Spectroscopy of Tissue XV., 1237606, Proceedings of SPIE. Progress in biomedical optics and imaging, vol. 12376, SPIE, Optical Tomography and Spectroscopy of Tissue XV 2023, San Francisco, United States, 30/01/23. https://doi.org/10.1117/12.2651676

High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy. / Dale, Robin; O’Sullivan, Thomas D.; Howard, Scott et al.
Optical Tomography and Spectroscopy of Tissue XV. ed. / Sergio Fantini; Paola Taroni. SPIE, 2023. 1237606 (Proceedings of SPIE. Progress in biomedical optics and imaging; Vol. 12376).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AU - Dehghani, Hamid

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AB - Frequency domain (FD) diffuse optical spectroscopy (DOS) can be used to recover absolute optical properties of biological tissue, providing valuable clinical feedback, including in diagnosis and monitoring of breast tumours. In this study, tomographic (3D) and topographic (2D) techniques for spatially-varying optical parameter recovery are presented, based on a multi-distance, handheld DOS probe. Processing pipelines and reconstruction quality are discussed and quantitatively compared, demonstrating the trade-offs between depth sensitivity, optical contrast, and computational speed. Together, the two techniques provide both depth sensitive real-time feedback, and high-resolution 3D reconstruction from a single set of measurements, enabling faster and more accurate clinical feedback.

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Dale R, O’Sullivan TD, Howard S, Campbell C, Orihuela-Espina F , Dehghani H. High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy. In Fantini S, Taroni P, editors, Optical Tomography and Spectroscopy of Tissue XV. SPIE. 2023. 1237606. (Proceedings of SPIE. Progress in biomedical optics and imaging). doi: 10.1117/12.2651676

High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy

Abstract

Publication series

Conference

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this