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Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
Bernadette Carroll
, Dorothea Maetzel
, Oliver Dk Maddocks
, Gisela Otten
, Matthew Ratcliff
, Graham R Smith
, Elaine A Dunlop
, João F Passos
, Owen R Davies
, Rudolf Jaenisch
, Andrew R Tee
,
Sovan Sarkar
, Viktor I Korolchuk
Cancer and Genomic Sciences
Research output
:
Contribution to journal
›
Article
›
peer-review
88
Citations (Scopus)
203
Downloads (Pure)
Overview
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Dive into the research topics of 'Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity'. Together they form a unique fingerprint.
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Keyphrases
Tuberous Sclerosis Complex
100%
Arginine
100%
Mammalian Target of Rapamycin (mTOR)
100%
Signaling Axis
100%
Rheb
100%
Amino Acids
20%
Growth Factors
20%
Lysosome
20%
Human Embryonic Stem Cells (hESCs)
20%
Early Development
10%
Metabolism
10%
Fibroblasts
10%
Hepatocytes
10%
Tight
10%
Dissociation
10%
Spatial Regulation
10%
Temporal Regulation
10%
Small GTP-binding Proteins
10%
Mitogen
10%
Lysosomal Localization
10%
Cellular Proteins
10%
Growth Factor Signaling
10%
Protein Homeostasis
10%
Intracellular Amino Acids
10%
TSC Complex
10%
Signaling Hub
10%
Mammalian Embryogenesis
10%
Arginine Sensing
10%
Allosteric Inhibition
10%
Available Pool
10%
Biochemistry, Genetics and Molecular Biology
TSC2
100%
Arginine
100%
Mammalian Target of Rapamycin Complex 1
100%
Amino Acids
20%
Lysosome
20%
Embryonic Stem Cell
20%
Metabolic Pathway
10%
Fibroblast
10%
Hepatocyte
10%
Growth Factor
10%
Embryogenesis
10%
Essential Amino Acid
10%
Protein Homeostasis
10%
Small GTPase
10%
Growth Factor Signaling
10%
Medicine and Dentistry
Arginine
100%
Mammalian Target of Rapamycin Complex 1
100%
Amino Acid
20%
Growth Factor
20%
Lysosome
20%
Human Embryonic Stem Cell
20%
Hepatocyte
10%
Mitogenic Agent
10%
Fibroblast
10%
Embryo Development
10%
Cell Protein
10%
Rheb Protein
10%
Protein Homeostasis
10%
Essential Amino Acid
10%
Diseases
10%
Small GTPase
10%
Neuroscience
Arginine
100%
Mammalian Target of Rapamycin Complex 1
100%
Growth Factor
20%
Amino Acid
20%
Embryonic Stem Cell
20%
Lysosome
20%
Metabolic Pathway
10%
Fibroblast
10%
GTPase
10%
Cell Protein
10%
Essential Amino Acid
10%
Rheb Protein
10%
Immunology and Microbiology
Mammalian Target of Rapamycin Complex 1
100%
Arginine
100%
Lysosome
20%
Growth Factor
20%
Human Embryonic Stem Cell
20%
Amino Acid
20%
Fibroblast
10%
Mitogen
10%
Embryo Development
10%
Protein Homeostasis
10%
Essential Amino Acid
10%
Pharmacology, Toxicology and Pharmaceutical Science
Arginine
100%
Mammalian Target of Rapamycin Complex 1
100%
Growth Factor
20%
Amino Acid
20%
Guanosine Triphosphatase
10%
Mitogenic Agent
10%
Cell Protein
10%
Essential Amino Acid
10%
Rheb Protein
10%
Diseases
10%