Does aerobic glycolysis exaggerate age related neutrophil dysfunction in community acquired pneumonia and sepsis: time for a new therapeutic strategy?

Thickett, David (Principal Investigator)

Inflammation and Ageing

Short title	Does aerobic glycolysis exaggerate age related neutrophil dysfunction in community acquired pneumonia and sepsis: time for a new therapeutic strategy?
Status	Finished
Effective start/end date	1/11/19 → 10/02/24

Funding

THE DUNHILL MEDICAL TRUST

2 Article

E-cigarette vapor renders neutrophils dysfunctional due to filamentous actin accumulation
Jasper, A., Faniyi, A., Davis, L., Grudzinska, F., Halston, R., Hazeldine, J., Parekh, D., Sapey, E., Thickett, D. & Scott, A., 4 Jan 2024, In: Journal of Investigational Allergology and Clinical Immunology. 153, 1, p. 320-329.e8
Research output: Contribution to journal › Article › peer-review

Open Access
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Observational cohort study protocol: neutrophil function and energetics in adults with pneumonia and sepsis: Pneumonia Metabolism in Ageing (PUMA)
Grudzinska, F. S., Faniyi, A. A., Scott, A., Sapey, E. & Thickett, D. R., 12 Oct 2023, In: BMJ Open Respiratory Research. 10, 1, 7 p., e001806.
Research output: Contribution to journal › Article › peer-review

Open Access
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10 Downloads (Pure)