Saverio Brogna

Accepting PhD Students

PhD projects

Saverio Brogna’s research focuses on RNA processing and translation. His group is interested in several aspects of RNA processing, and studies them primarily in the yeast Schizosaccharomyces pombe and the fruit fly Drosophila melanogaster because of their genetic advantages. One of our main concerns is the mechanism of nonsense mediated mRNA decay (NMD) - a translation-coupled process that plays an important role in quality control of gene expression by degrading abnormal mRNAs carrying premature termination codons (PTCs). A second concern of Dr Brogna’s research is the development of techniques to visualise the recruitment of processing factors to nascent transcripts and a third interest is in the visualisation of translation. Applications for PhD positions are welcome at any time.