Chris Tselepis

Prof

Accepting PhD Students

PhD projects

Chris Tselepis’ research interests are in the field of iron metabolism and gastrointestinal cancer, in particular oesophageal adenocarcinoma and colorectal cancer. Utilising several model systems and state-of-the-art technologies including proteomics and metabolomics, his research group has shown that excessive iron can exacerbate carcinogenesis through the modulation of multiple oncogenic signalling pathways. Through Cancer Research UK funding, the group is further exploring the role of haem metabolism in gastrointestinal cancers. In addition, with funding through the World Cancer Research Fund, it is beginning to explore the role of obesity in colorectal cancer, with a particular focus on the effect of adipokines on iron metabolism and ultimately cancer. Dr Tselepis’ goals are directed at iron chelation therapies as a mechanism of preventing gastrointestinal disease and overcoming resistance to chemotherapy.

20002023

Research activity per year

Network

University of Birmingham

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King’s College London

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Nottingham University Hospitals NHS Trust

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University of Otago

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Walsall Hospitals NHS Trust

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Ghent University

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University of Oxford

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Semmelweis University

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University of Sydney

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University of Nottingham

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New Cross Hospital

External organisation: Unknown

MRC Health Data Research UK

External organisation: Medical Research Council (MRC)xxxx

Assiut University

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University of Wolverhampton

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