Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort

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Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is a common cause of abnormal LFTs in primary care, but there are no data defining its contribution nor reporting the range of NAFLD severity in this setting. This study seeks to calculate the range of disease severity of NAFLD in a primary care setting. Methods: Adult patients with incidental abnormal LFTs, in the absence of a previous history, or current symptoms/ signs of liver disease were prospectively recruited from eight primary care practices in Birmingham. NAFLD was diagnosed as fatty liver on ultrasound, negative serological liver aetiology screen, and alcohol consumption 0.676) suggesting the presence of advanced liver fibrosis was found in 7.6% of NAFLD subjects, whereas 57.2% of NAFLD patients had a low NFS (


Original languageEnglish
Pages (from-to)234-240
Number of pages7
JournalJournal of Hepatology
Issue number1
Publication statusPublished - 1 Jan 2012


  • Non-alcoholic fatty liver, Fibrosis, Liver function test, Primary care