Pharmacological inhibition of aberrant transcription factor complexes in inversion 16 acute myeloid leukemia

Research output: Contribution to journalEditorial

Authors

Colleges, School and Institutes

External organisations

  • Cancer Bioinfomatics Group, Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

Abstract

Within the hematopoietic system, core binding factor beta (CBFβ) normally forms a complex with the master hematopoietic regulator, RUNX1 (1) and stabilizes its binding to DNA (2).

Details

Original languageEnglish
Article number30
Number of pages5
JournalStem Cell Investigation
Volume5
Publication statusPublished - 30 Sep 2018