TY - JOUR
T1 - International consensus on the clinical management of Inflammatory Breast Cancer from the Morgan Welch Inflammatory Breast Cancer research program 10th anniversary conference
AU - Ueno, Naoto T.
AU - Espinosa Fernandez, Jose Rodrigo
AU - Cristofanilli, Massimo
AU - Overmoyer, Beth
AU - Rea, Daniel
AU - El-Shinawi, Mohamad
AU - Berditchevski, Fedor
AU - Bellon, Jennifer
AU - Le-Petross, Huong T.
AU - Lucci, Anthony
AU - Babiera, Gildy
AU - DeSnyder, Sarah M.
AU - Teshome, Mediget
AU - Chang, Edward
AU - Lim, Bora
AU - Krishnamurthy, Savitri
AU - Stauder, Michael C.
AU - Parmar, Simrit
AU - Mohamed, Mona M.
AU - Alexander, Angela
AU - Valero, Vicente
AU - Woodward, Wendy A.
PY - 2018/4/6
Y1 - 2018/4/6
N2 - National and international experts in inflammatory breast cancer (IBC) from high-volume centers treating IBC recently convened at the 10th Anniversary Conference of the Morgan Welch Inflammatory Breast Cancer Research Program at The University of Texas MD Anderson Cancer Center in Houston Texas. A consensus on the clinical management of patients with IBC was discussed, summarized, and subsequently reviewed. All participants at the conference (patients, advocates, researchers, trainees, and clinicians) were queried using the MDRing electronic survey on key management issues. A summary of the expert consensus and participant voting is presented. Bilateral breast and nodal evaluation, breast magnetic resonance imaging, positron emission tomography/computed tomography, and medical photographs were endorsed as optimal. Neoadjuvant systemic therapy, modified radical mastectomy and level I and II ipsilateral axillary node dissection, post-mastectomy radiotherapy, adjuvant targeted therapy and hormonal therapy as indicated, and delayed reconstruction were agreed-upon fundamental premises of standard non-protocol-based treatment for IBC. Consideration for local-regional therapy in de novo stage IV IBC was endorsed to provide local control whenever feasible. Variation across centers and special circumstances were discussed.
AB - National and international experts in inflammatory breast cancer (IBC) from high-volume centers treating IBC recently convened at the 10th Anniversary Conference of the Morgan Welch Inflammatory Breast Cancer Research Program at The University of Texas MD Anderson Cancer Center in Houston Texas. A consensus on the clinical management of patients with IBC was discussed, summarized, and subsequently reviewed. All participants at the conference (patients, advocates, researchers, trainees, and clinicians) were queried using the MDRing electronic survey on key management issues. A summary of the expert consensus and participant voting is presented. Bilateral breast and nodal evaluation, breast magnetic resonance imaging, positron emission tomography/computed tomography, and medical photographs were endorsed as optimal. Neoadjuvant systemic therapy, modified radical mastectomy and level I and II ipsilateral axillary node dissection, post-mastectomy radiotherapy, adjuvant targeted therapy and hormonal therapy as indicated, and delayed reconstruction were agreed-upon fundamental premises of standard non-protocol-based treatment for IBC. Consideration for local-regional therapy in de novo stage IV IBC was endorsed to provide local control whenever feasible. Variation across centers and special circumstances were discussed.
KW - BCS
KW - Inflammatory breast cancer
KW - Management
KW - Mastectomy
KW - Neoadjuvant chemotherapy
KW - Radiation
UR - http://www.scopus.com/inward/record.url?scp=85045246520&partnerID=8YFLogxK
U2 - 10.7150/jca.23969
DO - 10.7150/jca.23969
M3 - Article
AN - SCOPUS:85045246520
SN - 1837-9664
VL - 9
SP - 1437
EP - 1447
JO - Journal of Cancer
JF - Journal of Cancer
IS - 8
ER -