Research output per year
Research output per year
Prof
Accepting PhD Students
PhD projects
Chris Bunce directs a translational research group dedicated to the development of novel therapies for leukaemias and lymphomas. A particular focus is the exploitation of drug redeployment strategies using off-patent drugs to provide affordable therapies that can be exploited by all, including the world's poorer nations.
A particular focus in Professor Bunce’s translational leukaemia and lymphoma research is the use of old drugs for new diseases. Drug redeployment endeavours to use relatively cheap available drugs and to use them in new ways. His group's approach is to take drugs that are not considered as anti-cancer drugs and to use them in combinations that generate an anti-cancer effect. The group's most advanced project is the use of the contraceptive drug medroxyprogesterone acetate combined with a cholesterol lowering drug Bezafibrate. This remarkable drug combination is now in clinical trials for the treatment of acute myeloid leukemia here in the UK and for Burkitt lymphoma in Malawi.
Research activity per year
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Gkoutos, G., Drayson, M. & Bunce, C.
19/09/22 → 31/05/26
Project: Research
1/10/19 → 30/09/24
Project: Research Councils
Bunce, C., Richter, A., Pratt, G., Khanim, F. & Gkoutos, G.
1/09/24 → 31/08/29
Project: Research
Drayson, M., Khanim, F., Kearns, P. & Bunce, C.
3/04/24 → 30/09/26
Project: Research
14/05/15
1 Media contribution
Press/Media: Press / Media