Yersinia pseudotuberculosis is resistant to killing by human neutrophils

Thomas R Laws, Martin S Davey, Christopher Green, Ian A M Cooper, Richard W Titball, Roman A Lukaszewski

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


The interaction between human neutrophils and the Gram negative gastrointestinal pathogen Yersinia pseudotuberculosis was investigated in vitro. Despite the wealth of data describing how Yersinia can affect the function of neutrophils, there are no published studies describing if neutrophil cells can affect the viability of Y. pseudotuberculosis. The wild-type IP32953 strain of Y. pseudotuberculosis was found to be resistant to killing by human neutrophils. Confocal examination and flow-cytometric analysis of this interaction revealed that bacteria were taken up.

Original languageEnglish
Pages (from-to)607-11
Number of pages5
JournalMicrobes and Infection
Issue number6
Publication statusPublished - Jun 2011


  • Endocytosis
  • Flow Cytometry
  • Humans
  • Microbial Viability
  • Microscopy, Confocal
  • Neutrophils
  • Yersinia pseudotuberculosis


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