What is the evidence that a pharmacy team working in an acute or emergency medicine department improves outcomes for patients: A systematic review

Ekta Punj*, Abbie Collins, Nirlep Agravedi, John Marriott, Elizabeth Sapey

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

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Abstract

Pharmacy services within hospitals are changing, with more taking on medication reconciliation activities. This systematic review was conducted to determine the measured impacts of Pharmacy teams working in an acute or emergency medicine department. The protocol followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was prospectively registered on PROSPERO, National Institute for Health and Care Research, UK registration number: CRD42020187487. The systematic review had two co-primary aims: a reduction in the number of incorrect prescriptions on admission by comparing the medication list from primary care to secondary care, and a reduction in the severity of harm caused by these incorrect prescriptions; chosen to determine the impact of pharmacy-led medication reconciliation services in the emergency and acute medicine setting. Seventeen articles were included. Fifteen were non-randomized controlled trials and two were randomized controlled trials. The number of patients combined for all studies was 7630. No studies included were based within the UK. All studies showed benefits in terms of a reduction in medicine errors and patient harm, compared to control arms. Nine articles were included in a statistical analysis comparing the pharmacy intervention arm with the non-pharmacy control arm, with a Chi2 of 101.10 and I2 value = 92%. However, studies were heterogenous with different outcome measures and many showed evidence of bias. The included studies consistently indicated that pharmacy services based within acute or emergency medicine departments in hospitals were associated with fewer medication errors. Further studies are needed to understand the health and economic impact of deploying a pharmacy service in acute medical settings including out-of-hours working.

Original languageEnglish
Article numbere01007
JournalPharmacology Research and Perspectives
Volume10
Issue number5
Early online date14 Sept 2022
DOIs
Publication statusPublished - Oct 2022

Bibliographical note

© 2022 The Authors. Pharmacology Research & Perspectives published by British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics and John Wiley & Sons Ltd.

Keywords

  • Emergency Medicine
  • Humans
  • Medication Errors/prevention & control
  • Medication Reconciliation/methods
  • Pharmaceutical Services
  • emergency medicine
  • medication reconciliation
  • medication errors
  • pharmac*

ASJC Scopus subject areas

  • Neurology
  • Pharmacology, Toxicology and Pharmaceutics(all)

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