Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis

Roeland Zoutendijk; Jurrien Gp Reijnders; Fabien Zoulim; Ashley Brown; David J Mutimer; Katja Deterding; Wolf Peter Hofmann; Joerg Petersen; Massimo Fasano; Maria Buti; Thomas Berg; Bettina E Hansen; Milan J Sonneveld; Heiner Wedemeyer; Harry L A Janssen; VIRGIL Surveillance Study Group

doi:10.1136/gutjnl-2012-302024

Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis

Roeland Zoutendijk, Jurrien Gp Reijnders, Fabien Zoulim, Ashley Brown, David J Mutimer, Katja Deterding, Wolf Peter Hofmann, Joerg Petersen, Massimo Fasano, Maria Buti, Thomas Berg, Bettina E Hansen, Milan J Sonneveld, Heiner Wedemeyer, Harry L A Janssen, VIRGIL Surveillance Study Group

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

126 Citations (Scopus)

Abstract

Entecavir (ETV) is a potent inhibitor of viral replication in chronic hepatitis B and prolonged treatment may result in regression of fibrosis. The aim of this study was to investigate the effect of ETV on disease progression.

Original language	English
Pages (from-to)	760-5
Number of pages	6
Journal	Gut
Volume	62
Issue number	5
DOIs	https://doi.org/10.1136/gutjnl-2012-302024
Publication status	Published - May 2013

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Zoutendijk, R., Reijnders, J. G., Zoulim, F., Brown, A., Mutimer, D. J., Deterding, K., Hofmann, W. P., Petersen, J., Fasano, M., Buti, M., Berg, T., Hansen, B. E., Sonneveld, M. J., Wedemeyer, H., Janssen, H. L. A., & VIRGIL Surveillance Study Group (2013). Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis. Gut, 62(5), 760-5. https://doi.org/10.1136/gutjnl-2012-302024

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title = "Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis",

abstract = "Entecavir (ETV) is a potent inhibitor of viral replication in chronic hepatitis B and prolonged treatment may result in regression of fibrosis. The aim of this study was to investigate the effect of ETV on disease progression.",

author = "Roeland Zoutendijk and Reijnders, {Jurrien Gp} and Fabien Zoulim and Ashley Brown and Mutimer, {David J} and Katja Deterding and Hofmann, {Wolf Peter} and Joerg Petersen and Massimo Fasano and Maria Buti and Thomas Berg and Hansen, {Bettina E} and Sonneveld, {Milan J} and Heiner Wedemeyer and Janssen, {Harry L A} and {VIRGIL Surveillance Study Group}",

year = "2013",

month = may,

doi = "10.1136/gutjnl-2012-302024",

language = "English",

volume = "62",

pages = "760--5",

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Zoutendijk, R, Reijnders, JG, Zoulim, F, Brown, A, Mutimer, DJ, Deterding, K, Hofmann, WP, Petersen, J, Fasano, M, Buti, M, Berg, T, Hansen, BE, Sonneveld, MJ, Wedemeyer, H, Janssen, HLA & VIRGIL Surveillance Study Group 2013, 'Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis', Gut, vol. 62, no. 5, pp. 760-5. https://doi.org/10.1136/gutjnl-2012-302024

TY - JOUR

T1 - Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis

AU - Zoutendijk, Roeland

AU - Reijnders, Jurrien Gp

AU - Zoulim, Fabien

AU - Brown, Ashley

AU - Mutimer, David J

AU - Deterding, Katja

AU - Hofmann, Wolf Peter

AU - Petersen, Joerg

AU - Fasano, Massimo

AU - Buti, Maria

AU - Berg, Thomas

AU - Hansen, Bettina E

AU - Sonneveld, Milan J

AU - Wedemeyer, Heiner

AU - Janssen, Harry L A

AU - VIRGIL Surveillance Study Group

PY - 2013/5

Y1 - 2013/5

N2 - Entecavir (ETV) is a potent inhibitor of viral replication in chronic hepatitis B and prolonged treatment may result in regression of fibrosis. The aim of this study was to investigate the effect of ETV on disease progression.

AB - Entecavir (ETV) is a potent inhibitor of viral replication in chronic hepatitis B and prolonged treatment may result in regression of fibrosis. The aim of this study was to investigate the effect of ETV on disease progression.

U2 - 10.1136/gutjnl-2012-302024

DO - 10.1136/gutjnl-2012-302024

M3 - Article

C2 - 22490523

SN - 1468-3288

VL - 62

SP - 760

EP - 765

JO - Gut

JF - Gut

IS - 5

ER -

Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis

Abstract

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