Use of and microbial resistance to antibiotics in China: a path to reducing antimicrobial resistance

Dan Cui, Xinliang Liu, Peter Hawkey, Hao-Ying Li, Quan Wang, Zongfu Mao, Jing Sun

Research output: Contribution to journalReview articlepeer-review

16 Citations (Scopus)
158 Downloads (Pure)


We analyzed China's current use of and microbial resistance to antibiotics, and possible means of reducing antimicrobial resistance. Interventions like executive orders within clinical settings and educational approach with vertical approaches rather than an integrated strategy to curb the use of antimicrobials remain limited. An underlying problem is the system of incentives that has resulted in the intensification of inappropriate use by health professionals and patients. There is an urgent need to explore the relationship between financial and non-financial incentives for providers and patients, to eliminate inappropriate incentives. China's national health reforms have created an opportunity to contain inappropriate use of antibiotics through more comprehensive and integrated strategies. Containment of microbial resistance may be achieved by strengthening surveillance at national, regional and hospital levels; eliminating detrimental incentives within the health system; and changing prescribing behaviors to a wider health systems approach, to achieve long-term, equitable and sustainable results and coordinate stakeholders' actions through transparent sharing of information.

Original languageEnglish
Pages (from-to)1768-1778
Number of pages11
JournalJournal of International Medical Research
Issue number6
Early online date30 Jan 2017
Publication statusPublished - 1 Dec 2017


  • Anti-Bacterial Agents/pharmacology
  • China
  • Drug Resistance
  • Humans
  • Prescription Drugs/pharmacology
  • Bacterial/drug effects
  • antimicrobial resistance
  • containment
  • appropriate use


Dive into the research topics of 'Use of and microbial resistance to antibiotics in China: a path to reducing antimicrobial resistance'. Together they form a unique fingerprint.

Cite this