Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Keyphrases

• Activity Patterns 20%
• Autoregulatory Loop 100%
• B Cell Development 20%
• B Cells 100%
• Cell-to-cell 100%
• Cell-type-specific Gene Expression 20%
• Chromatin 20%
• Cis-element 60%
• Cis-regulatory Elements 20%
• Differential Activity 20%
• Hematopoietic Stem Cells 20%
• Leukemia 20%
• Lineage-specific 20%
• Macrophages 20%
• Molecular Analysis 20%
• Myeloid Cells 100%
• Novel Mechanism 20%
• Physiologic 20%
• PU.1 100%
• Specific Expression 20%
• Specific Pattern 20%
• Specific Transcription Factor 20%
• Targeted Deletion 20%
• Transcription Factor PU.1 20%
• Transgenic Study 20%

Immunology and Microbiology

• Autoregulation 50%
• B Cell 100%
• B Cell Development 50%
• Lineages 100%
• Macrophage 50%
• Myeloid 100%
• Regulatory Sequence 50%
• Transcription Factor PU 1 50%
• Transcription Factors 50%
• Transgenics 50%

Biochemistry, Genetics and Molecular Biology

• Autoregulation 33%
• B Cell 100%
• Cell Maturation 33%
• Cis-Regulatory Element 66%
• Cooperation 33%
• Macrophage 33%
• Myeloid 100%
• Regulatory Sequence 33%
• Transcription Factor PU 1 33%
• Transcription Factors 33%
• Transgenics 33%