Thiacetazone, an Antitubercular Drug that Inhibits Cyclopropanation of Cell Wall Mycolic Acids in Mycobacteria

Medicine & Life Sciences

• Thioacetazone 100%
• Mycolic Acids 90%
• Antitubercular Agents 87%
• Mycobacterium 62%
• Cell Wall 59%
• cyclopropane 36%
• Mycobacterium bovis 9%
• Mycobacterium tuberculosis 8%
• Magnetic Resonance Spectroscopy 7%
• Pharmaceutical Preparations 7%
• methionine methyl ester 7%
• Mycobacterium marinum 7%
• Thin Layer Chromatography 5%
• Immunomodulation 5%
• Complex Mixtures 4%
• Transferases 4%
• Mass Spectrometry 4%
• Permeability 3%
• Fatty Acids 3%
• Tuberculosis 3%
• Vaccines 3%
• Therapeutics 1%

Agriculture & Biology

• mycolic acids 82%
• Mycobacterium 63%
• antibiotics 43%
• cell walls 42%
• drugs 11%
• Mycobacterium tuberculosis 10%
• nuclear magnetic resonance spectroscopy 8%
• Mycobacterium marinum 7%
• Mycobacterium bovis BCG 6%
• immunomodulation 5%
• tuberculosis 5%
• long chain fatty acids 5%
• spinning 4%
• thin layer chromatography 4%
• transferases 4%
• cells 4%
• methionine 3%
• vaccines 3%
• mechanism of action 3%
• mass spectrometry 3%
• permeability 3%
• synthesis 2%
• methodology 1%

Chemistry

• Mycolic Acid 88%
• Tuberculostatic Agent 79%
• Cyclopropane 19%
• Mycolates 8%
• Mycolate 8%
• High Resolution Magic-Angle Spinning 6%
• Antitubercular Agent 6%
• NMR Spectroscopy 5%
• Cyclopropane Ring 5%
• Long-Chain Fatty Acid 5%
• Drug Target 5%
• Drug 4%
• Thin Layer Chromatography 4%
• Permeability 3%
• Double Bond 3%
• Strain 3%
• Mass Spectrometry 2%