TY - JOUR
T1 - The Theta-Gamma Neural Code
AU - Lisman, J.E.
AU - Jensen, O.
PY - 2013/3/20
Y1 - 2013/3/20
N2 - Theta and gamma frequency oscillations occur in the same brain regions and interact with each other, a process called cross-frequency coupling. Here, we review evidence for the following hypothesis: that the dual oscillations form a code for representing multiple items in an ordered way. This form of coding has been most clearly demonstrated in the hippocampus, where different spatial information is represented in different gamma subcycles of a theta cycle. Other experiments have tested the functional importance of oscillations and their coupling. These involve correlation of oscillatory properties with memory states, correlation with memory performance, and effects of disrupting oscillations on memory. Recent work suggests that this coding scheme coordinates communication between brain regions and is involved in sensory as well as memory processes
AB - Theta and gamma frequency oscillations occur in the same brain regions and interact with each other, a process called cross-frequency coupling. Here, we review evidence for the following hypothesis: that the dual oscillations form a code for representing multiple items in an ordered way. This form of coding has been most clearly demonstrated in the hippocampus, where different spatial information is represented in different gamma subcycles of a theta cycle. Other experiments have tested the functional importance of oscillations and their coupling. These involve correlation of oscillatory properties with memory states, correlation with memory performance, and effects of disrupting oscillations on memory. Recent work suggests that this coding scheme coordinates communication between brain regions and is involved in sensory as well as memory processes
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84875515072&partnerID=MN8TOARS
U2 - 10.1016/j.neuron.2013.03.007
DO - 10.1016/j.neuron.2013.03.007
M3 - Article
SN - 0896-6273
VL - 77
SP - 1002
EP - 1016
JO - Neuron
JF - Neuron
IS - 6
ER -