Takayasu Arteritis and Atherosclerosis: Illustrating the Consequences of Endothelial Damage

A Filer, D Nicholls, R Corston, P Carey, Paul Bacon

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The excess of cardiovascular morbidity associated with chronic vasculitic disease has become a focus of considerable research, particularly regarding the link between endothelial damage and the development of atherosclerosis. We describe a case of Takayasu arteritis treated sub-optimally by today's standards, giving rise to an 11 year history of progressive, stepwise decline associated with cerebrovascular events and leading to early death. Postmortem findings presented a picture of chronic atherosclerotic disease but in a distribution consistent with lesions of Takayasu arteritis.
Original languageEnglish
Pages (from-to)2752-3
Number of pages2
JournalThe Journal of Rheumatology
Volume28
Publication statusPublished - 1 Jan 2001

Keywords

  • endothelium
  • endothelial dysfunction
  • vasculitis
  • atherosclerosis
  • Takayasu's arteritis

Fingerprint

Dive into the research topics of 'Takayasu Arteritis and Atherosclerosis: Illustrating the Consequences of Endothelial Damage'. Together they form a unique fingerprint.

Cite this