TY - JOUR
T1 - Synthesis of threitol ceramide and [C-14]threitol ceramide, non-glycosidic analogues of the potent CD1d antigen alpha-galactosyl ceramide
AU - Diaz, YRG
AU - Wojno, J
AU - Cox, Liam
AU - Besra, Gurdyal
PY - 2009/5/1
Y1 - 2009/5/1
N2 - The synthesis of threitol ceramide, which is a non-glycosidic analogue of the potent CD1d antigen alpha-galactosyl ceramide, is described. The synthesis of a C-14-labelled threitol ceramide analogue is also presented. This radiolabelled analogue will allow the intracellular trafficking pattern/itinerary of this iNKT-CD1d cell agonist to be studied. (C) 2009 Published by Elsevier Ltd.
AB - The synthesis of threitol ceramide, which is a non-glycosidic analogue of the potent CD1d antigen alpha-galactosyl ceramide, is described. The synthesis of a C-14-labelled threitol ceramide analogue is also presented. This radiolabelled analogue will allow the intracellular trafficking pattern/itinerary of this iNKT-CD1d cell agonist to be studied. (C) 2009 Published by Elsevier Ltd.
U2 - 10.1016/j.tetasy.2009.02.020
DO - 10.1016/j.tetasy.2009.02.020
M3 - Article
VL - 20
SP - 747
EP - 753
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
IS - 6-8
ER -