Abstract
Molecules such as knots and catenanes can exhibit topological chirality resulting from their entangled nature. Controlling the handedness of this chirality, especially beyond the simplest systems, is a significant synthetic challenge. In this issue of Chem, Zhang and co-workers have realized the stereoselective synthesis of both a cinquefoil (51) knot and a triply braided, Star of David [2]catenane (621 link). Gaining such control over these higher-order molecular entanglements expands their potential use in sensing, catalysis, and materials applications.
Original language | English |
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Journal | Chem |
Early online date | 22 Mar 2023 |
DOIs | |
Publication status | E-pub ahead of print - 22 Mar 2023 |