Requirements for effective antitumor responses of TCR transduced T cells

Keyphrases

• T Cells 100%
• Engineered T Cells 100%
• Anti-tumor Response 100%
• Tumor 60%
• Clinical Trials 20%
• Vaccination 20%
• Reduced Expression 20%
• Precursor Frequency 20%
• Selective Pressure 20%
• Specific T Cells 20%
• Adoptive Transfer 20%
• Antitumor Activity 20%
• Irradiation 20%
• Vaccine Response 20%
• Induced Activation 20%
• Antigen-specific T Cell Response 20%
• Ag-specific 20%
• Genetically Modified T Cells 20%
• Gene Transfer 20%
• Tumor-specific T Cells 20%
• In Vivo Efficacy 20%
• TCR Gene Therapy 20%
• Simultaneous Targeting 20%
• TCR Expression 20%
• Gene-modified T Cells 20%
• Adoptive Cell Transfer 20%
• TCR Sequencing 20%
• In Vivo Antitumor Activity 20%
• Feasible Strategy 20%
• Genetic Optimization 20%
• Antitumor Potential 20%

Biochemistry, Genetics and Molecular Biology

• T Cell 100%
• T Cell Receptor 100%
• Antineoplastic Activity 18%
• Precursor 9%
• Gene Therapy 9%
• Genetics 9%
• Clinical Trial 9%
• Conditioning 9%

Immunology and Microbiology

• T Cell 100%
• T Cell Receptor 100%
• Antineoplastic Activity 18%
• Precursor 9%
• Conditioning 9%
• Gene Transfer 9%
• Transfer Cell 9%