Repeat-element driven activation of proto-oncogenes in human malignancies

B Lamprecht, Constanze Bonifer, S Mathas

Research output: Contribution to journalArticle

11 Citations (Scopus)


Recent data demonstrated that the aberrant activity of endogenous repetitive elements of the DNA in humans can drive the expression of proto-oncogenes. This article summarizes these results and gives an outlook on the impact of these findings on the pathogenesis and therapy of human cancer.
Original languageEnglish
Pages (from-to)4276-4281
Number of pages6
JournalCell Cycle
Issue number21
Publication statusPublished - 1 Nov 2010


  • DNA methylation
  • LTR
  • Hodgkin lymphoma
  • epigenetic reprogramming
  • CSF-1 receptor

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology


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