Relationships between age at diagnosis, clinical features, and outcome of therapy in children treated in the Medical Research Council AML10 and 12 trials for acute myeloid leukemia

DKH Webb, G Harrison, RF Stevens, BG Gibson, IM Hann, Keith Wheatley

Research output: Contribution to journalArticle

116 Citations (Scopus)

Abstract

Between May 1988 and June 2000, 698 children were treated in the Medical Research Council acute myeloid leukemia 10 and 12 trials. The presenting features and outcomes of therapy in these children were compared by age. Although there was no single cutoff in age, younger children were more likely to have intermediate risk and less likely to have favorable cytogenetics (P
Original languageEnglish
Pages (from-to)1714-1720
Number of pages7
JournalBlood
Volume98
Issue number6
DOIs
Publication statusPublished - 15 Sep 2001

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