TY - JOUR
T1 - -related anthropometric remodelling resulting in increased and redistributed adiposity is associated with increases in the prevalence of cardiovascular risk factors in Chinese subjects
AU - Thomas, Graham
AU - Tomlinson, B
AU - Hong, AWL
AU - Hui, SSC
PY - 2006/1/1
Y1 - 2006/1/1
N2 - BACKGROUND: Ageing promotes increases in the prevalence of components of the metabolic syndrome, which obesity often underlies. METHODS: We report the relationship between ageing, obesity and other cardiovascular risk factors in 694 community-based Chinese subjects in gender-specific groups of three age ranges: 20.0-39.9 (young), 40.0-59.9 (middle-aged) and 60.0-79.9 (old-aged) years. RESULTS: Body mass index (BMI) values were similar in males in each age group, but waist and percentage body fat increased (6.6, and 39.5%, both p <0.001, respectively), from young to old-age groups, as did blood pressure and glycated haemoglobin levels (all p <0.001). In the females, increases (all p <0.001) in percentage body fat (29.3%) were accompanied by greater increases in BMI (10.3%) and waist (19.2%) than the males. Blood pressure, glycated haemoglobin, total and LDL-cholesterol and triglyceride levels increased linearly with age (all p <0.001). CONCLUSION: Age-related increases in central adiposity and percentage body fat were associated with increasingly adverse cardiovascular risk factor profiles.
AB - BACKGROUND: Ageing promotes increases in the prevalence of components of the metabolic syndrome, which obesity often underlies. METHODS: We report the relationship between ageing, obesity and other cardiovascular risk factors in 694 community-based Chinese subjects in gender-specific groups of three age ranges: 20.0-39.9 (young), 40.0-59.9 (middle-aged) and 60.0-79.9 (old-aged) years. RESULTS: Body mass index (BMI) values were similar in males in each age group, but waist and percentage body fat increased (6.6, and 39.5%, both p <0.001, respectively), from young to old-age groups, as did blood pressure and glycated haemoglobin levels (all p <0.001). In the females, increases (all p <0.001) in percentage body fat (29.3%) were accompanied by greater increases in BMI (10.3%) and waist (19.2%) than the males. Blood pressure, glycated haemoglobin, total and LDL-cholesterol and triglyceride levels increased linearly with age (all p <0.001). CONCLUSION: Age-related increases in central adiposity and percentage body fat were associated with increasingly adverse cardiovascular risk factor profiles.
U2 - 10.1002/dmrr.581
DO - 10.1002/dmrr.581
M3 - Article
C2 - 16021653
SN - 1520-7560
SN - 1520-7560
SN - 1520-7560
SN - 1520-7560
SN - 1520-7560
SN - 1520-7560
SN - 1520-7560
SN - 1520-7560
SN - 1520-7560
SN - 1520-7560
VL - 22
SP - 72
EP - 78
JO - Diabetes/metabolism research and reviews
JF - Diabetes/metabolism research and reviews
ER -