Abstract
The Rho family of small GTP binding proteins play a key part in regulating the actin cytoskeleton and cell adhesion through integrin receptors. In addition, these proteins regulate signal transduction pathways essential for normal cell growth. Many of the molecules that regulate Rho have oncogenic activity, suggesting that members of the Rho family may have an important role in tumour formation.
| Original language | English |
|---|---|
| Pages (from-to) | 311-22 |
| Number of pages | 12 |
| Journal | Cancer surveys |
| Volume | 27 |
| Publication status | Published - 1996 |