Regional adaptation defines sensitivity to future ocean acidification

Piero Calosi*, Sedercor Melatunan, Lucy M. Turner, Yuri Artioli, Robert L. Davidson, Jonathan J. Byrne, Mark R. Viant, Stephen Widdicombe, Simon D. Rundle

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)
145 Downloads (Pure)


Physiological responses to temperature are known to be a major determinant of species distributions and can dictate the sensitivity of populations to global warming. In contrast, little is known about how other major global change drivers, such as ocean acidification (OA), will shape species distributions in the future. Here, by integrating population genetics with experimental data for growth and mineralization, physiology and metabolomics, we demonstrate that the sensitivity of populations of the gastropod Littorina littorea to future OA is shaped by regional adaptation. Individuals from populations towards the edges of the natural latitudinal range in the Northeast Atlantic exhibit greater shell dissolution and the inability to upregulate their metabolism when exposed to low pH, thus appearing most sensitive to low seawater pH. Our results suggest that future levels of OA could mediate temperature-driven shifts in species distributions, thereby influencing future biogeography and the functioning of marine ecosystems.

Original languageEnglish
Article number13994
JournalNature Communications
Publication statusPublished - 9 Jan 2017


  • Climate-change ecology
  • Ecophysiology
  • Metabolomics
  • Population genetics

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)


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