Abstract
Pickering emulsions, stabilised by organic or inorganic particles, offer long-term dispersibility of liquid droplets and resistance to coalescence. The versatility of stabilising particles and their ability to encapsulate and release cargo with high internal payload capacity makes them attractive in a wide variety of applications, ranging from catalysis to the cosmetic and food industry. While these properties make them an equally promising material platform for pharmaceutical and clinical applications, the development of Pickering emulsions for healthcare is still in its infancy. Herein, we summarise and discuss recent progress in the development of Pickering emulsions for biomedical applications, probing their design for passive diffusion-based release as well as stimuli-responsive destabilisation. We further comment on challenges and future directions of this exciting and rapidly expanding area of research.
Original language | English |
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Pages (from-to) | 173-189 |
Number of pages | 17 |
Journal | Current Opinion in Colloid and Interface Science |
Volume | 39 |
DOIs | |
Publication status | Published - Feb 2019 |
Bibliographical note
Funding Information:The authors acknowledge financial support from the Engineering and Physical Sciences Research Council through the Centre for Doctoral Training in Advanced Therapeutics and Nanomedicines ( EP/L01646X , supporting CLGH) and the Centre for Doctoral Training in Molecular Modelling and Materials Science ( EP/L015862/1 , supporting MAP) in support of BASF SE.
Publisher Copyright:
© 2019 Elsevier Ltd
Keywords
- Biomedicine
- Pickering emulsions
- Stimuli-responsive
- Therapeutic delivery
ASJC Scopus subject areas
- Surfaces and Interfaces
- Physical and Theoretical Chemistry
- Polymers and Plastics
- Colloid and Surface Chemistry