Recent advances in designed coiled coils and helical bundles with inorganic prosthetic groups - from structural to functional applications

Anna F. A. Peacock

doi:10.1016/j.cbpa.2016.03.009

Recent advances in designed coiled coils and helical bundles with inorganic prosthetic groups - from structural to functional applications

Anna F. A. Peacock^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Review article › peer-review

20 Citations (Scopus)

Abstract

Recent contributions to the de novo design of metalloproteins based on coiled coils and helical bundles are described herein, with examples covering mononuclear, multinuclear, and metallo-porphyrin sites, as well as membrane soluble designs. Important progress is being made in the field with a diverse range of functionalities, sometimes beyond those found in biology, being successfully engineered into these simplified scaffolds and represents an exciting prospect for the future.

Original language	English
Pages (from-to)	160-165
Number of pages	6
Journal	Current Opinion in Chemical Biology
Volume	31
Early online date	28 Mar 2016
DOIs	https://doi.org/10.1016/j.cbpa.2016.03.009
Publication status	Published - 1 Apr 2016

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry

Access to Document

10.1016/j.cbpa.2016.03.009Licence: None: All rights reserved

https://www.sciencedirect.com/science/article/pii/S1367593116300187Licence: None: All rights reserved

Cite this

@article{b6190bc18b89458687a88dc8d771f731,

title = "Recent advances in designed coiled coils and helical bundles with inorganic prosthetic groups - from structural to functional applications",

abstract = "Recent contributions to the de novo design of metalloproteins based on coiled coils and helical bundles are described herein, with examples covering mononuclear, multinuclear, and metallo-porphyrin sites, as well as membrane soluble designs. Important progress is being made in the field with a diverse range of functionalities, sometimes beyond those found in biology, being successfully engineered into these simplified scaffolds and represents an exciting prospect for the future.",

author = "Peacock, {Anna F. A.}",

year = "2016",

month = apr,

day = "1",

doi = "10.1016/j.cbpa.2016.03.009",

language = "English",

volume = "31",

pages = "160--165",

journal = "Current Opinion in Chemical Biology",

issn = "1367-5931",

publisher = "Elsevier",

}

TY - JOUR

T1 - Recent advances in designed coiled coils and helical bundles with inorganic prosthetic groups - from structural to functional applications

AU - Peacock, Anna F. A.

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Recent contributions to the de novo design of metalloproteins based on coiled coils and helical bundles are described herein, with examples covering mononuclear, multinuclear, and metallo-porphyrin sites, as well as membrane soluble designs. Important progress is being made in the field with a diverse range of functionalities, sometimes beyond those found in biology, being successfully engineered into these simplified scaffolds and represents an exciting prospect for the future.

AB - Recent contributions to the de novo design of metalloproteins based on coiled coils and helical bundles are described herein, with examples covering mononuclear, multinuclear, and metallo-porphyrin sites, as well as membrane soluble designs. Important progress is being made in the field with a diverse range of functionalities, sometimes beyond those found in biology, being successfully engineered into these simplified scaffolds and represents an exciting prospect for the future.

UR - http://www.scopus.com/inward/record.url?scp=84961654003&partnerID=8YFLogxK

U2 - 10.1016/j.cbpa.2016.03.009

DO - 10.1016/j.cbpa.2016.03.009

M3 - Review article

C2 - 27031927

AN - SCOPUS:84961654003

SN - 1367-5931

VL - 31

SP - 160

EP - 165

JO - Current Opinion in Chemical Biology

JF - Current Opinion in Chemical Biology

ER -

Recent advances in designed coiled coils and helical bundles with inorganic prosthetic groups - from structural to functional applications

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this