TY - JOUR
T1 - Reading signals on the nucleosome with a new nomenclature for modified histones
AU - Turner, Bryan
PY - 2005/1/1
Y1 - 2005/1/1
N2 - The tails of the four core histones are exposed on the nucleosome surface, where they are subject to a variety of enzyme-catalyzed, post-translational modifications. Modifications, singly or in combination, provide a source of information that can be used for signal transduction during ongoing processes, such as transcription, or as heritable epigenetic marks. A nomenclature is presented that allows patterns of histone modification to be clearly and unambiguously specified and that should facilitate discussion of their functional roles.
AB - The tails of the four core histones are exposed on the nucleosome surface, where they are subject to a variety of enzyme-catalyzed, post-translational modifications. Modifications, singly or in combination, provide a source of information that can be used for signal transduction during ongoing processes, such as transcription, or as heritable epigenetic marks. A nomenclature is presented that allows patterns of histone modification to be clearly and unambiguously specified and that should facilitate discussion of their functional roles.
UR - http://www.scopus.com/inward/record.url?scp=15044358494&partnerID=8YFLogxK
U2 - 10.1038/nsmb0205-110
DO - 10.1038/nsmb0205-110
M3 - Article
C2 - 15702071
SN - 1545-9993
VL - 12
SP - 110
EP - 112
JO - Nature Structural and Molecular Biology
JF - Nature Structural and Molecular Biology
IS - 2
ER -