Rare non-Hodgkin lymphoma of childhood and adolescence: A consensus diagnostic and therapeutic approach to pediatric-type follicular lymphoma, marginal zone lymphoma, and nonanaplastic peripheral T-cell lymphoma

Andishe Attarbaschi*, Oussama Abla, Laura Arias Padilla, Auke Beishuizen, G. A.Amos Burke, Laurence Brugières, Julie Bruneau, Birgit Burkhardt, Emanuele S.G. d'Amore, Wolfram Klapper, Udo Kontny, Marta Pillon, Mary Taj, Suzanne D. Turner, Anne Uyttebroeck, Wilhelm Woessmann, Karin Mellgren

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Pediatric-type follicular (PTFL), marginal zone (MZL), and peripheral T-cell lymphoma (PTCL) account each for <2% of childhood non-Hodgkin lymphoma. We present clinical and histopathological features of PTFL, MZL, and few subtypes of PTCL and provide treatment recommendations. For localized PTFL and MZL, watchful waiting after complete resection is the therapy of choice. For PTCL, therapy is subtype-dependent and ranges from a block-like anaplastic large cell lymphoma (ALCL)-derived and, alternatively, leukemia-derived therapy in PTCL not otherwise specified and subcutaneous panniculitis-like T-cell lymphoma to a block-like mature B-NHL-derived or, preferentially, ALCL-derived treatment followed by hematopoietic stem cell transplantation in first remission in hepatosplenic and angioimmunoblastic T-cell lymphoma.

Original languageEnglish
Article numbere28416
JournalPediatric Blood and Cancer
Volume67
Issue number8
DOIs
Publication statusPublished - 1 Aug 2020

Bibliographical note

Publisher Copyright:
© 2020 Wiley Periodicals, Inc.

Keywords

  • follicular lymphoma
  • marginal zone lymphoma
  • non-Hodgkin lymphoma
  • peripheral T-cell lymphoma
  • rare

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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