TY - JOUR
T1 - Plasma levels of vascular endothelial growth factor and its soluble receptor (sFlt-1) in essential hypertension
AU - Belgore, Funmilayo
AU - Blann, Andrew
AU - Li-Saw-Hee, FL
AU - Beevers, David
AU - Lip, Gregory
PY - 2001/3/15
Y1 - 2001/3/15
N2 - In this study of 27 untreated patients with uncomplicated essential hypertension, we report on elevated plasma levels of vascular endothelial growth factor and its soluble receptor FIt-1 compared with healthy controls; these increased levels are reduced by the treatment of hypertension. This raises the possibility that abnormal angiogenesis may contribute to the pathogenesis of complications related to hypertension and merits exploration in larger studies.
AB - In this study of 27 untreated patients with uncomplicated essential hypertension, we report on elevated plasma levels of vascular endothelial growth factor and its soluble receptor FIt-1 compared with healthy controls; these increased levels are reduced by the treatment of hypertension. This raises the possibility that abnormal angiogenesis may contribute to the pathogenesis of complications related to hypertension and merits exploration in larger studies.
UR - http://www.scopus.com/inward/record.url?scp=0035869145&partnerID=8YFLogxK
U2 - 10.1016/S0002-9149(00)01512-5
DO - 10.1016/S0002-9149(00)01512-5
M3 - Article
C2 - 11249912
SN - 1879-1913
VL - 87
SP - 805
EP - 807
JO - The American Journal of Cardiology
JF - The American Journal of Cardiology
IS - 6
ER -