Abstract
The present study determined the detailed pharmacological profile of heterologously expressed human (h) homomeric 5-HT3A receptors in direct comparison to heteromeric h5-HT3A/3B receptors. The very minor differences in their respective pharmacological profiles indicates that the 5-HT3B receptor subunit alters, predominantly, the biophysical rather than the pharmacological properties of the 5-HT3 receptor. (C) 2001 Elsevier Science Ltd. All rights reserved.
Original language | English |
---|---|
Pages (from-to) | 282-284 |
Number of pages | 3 |
Journal | Neuropharmacology |
Volume | 41 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1 Aug 2001 |
Keywords
- 5-HT3 receptor
- 5-HT3B subunit
- ligand-gated ion channel
- 5-HT3A subunit