Nanofocused synchrotron x-ray absorption studies of the intracellular redox state of an organometallic complex in cancer cells

Carlos Sanchez-Cano, Diego Gianolio, Isolda Romero-Canelón, Remi Tucoulou, Peter J. Sadler

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)
88 Downloads (Pure)

Abstract

Synchrotron nanoprobe X-ray absorption (XAS) studies of a potent organo-osmium arene anticancer complex in ovarian cancer cells at subcellular resolution allow detection and quantification of both Os II and Os III species, which are distributed heterogeneously in different areas of the cells.

Original languageEnglish
Pages (from-to)7065-7068
Number of pages4
JournalChemical Communications
Volume55
Issue number49
Early online date31 May 2019
DOIs
Publication statusPublished - 21 Jun 2019

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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