Abstract
To examine the role of mitogen-activated protein kinase-activated protein kinase 2 (MK2) in mediating the cellular response to pro-inflammatory cytokines in human primary osteoarthritis (OA) chondrocytes.
Original language | English |
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Pages (from-to) | 124-31 |
Number of pages | 8 |
Journal | Osteoarthritis and Cartilage |
Volume | 17 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 2009 |
Keywords
- Adenoviridae
- Peptide Hydrolases
- Enzyme Activation
- Intracellular Signaling Peptides and Proteins
- Humans
- Cartilage, Articular
- Aged
- Chondrocytes
- Interleukin-1beta
- RNA, Small Interfering
- Protein-Serine-Threonine Kinases
- Osteoarthritis, Knee
- Dinoprostone
- MAP Kinase Signaling System
- Phosphorylation
- Transfection
- Cells, Cultured
- Genetic Vectors
- Middle Aged
- Male