TY - JOUR
T1 - Mass spectrometry in systems biology an introduction
AU - Dunn, Warwick B
N1 - Copyright © 2011 Elsevier Inc. All rights reserved.
PY - 2011
Y1 - 2011
N2 - The qualitative detection, quantification, and structural characterization of analytes in biological systems are important requirements for objectives to be fulfilled in systems biology research. One analytical tool applied to a multitude of systems biology studies is mass spectrometry, particularly for the study of proteins and metabolites. Here, the role of mass spectrometry in systems biology will be assessed, the advantages and disadvantages discussed, and the instrument configurations available described. Finally, general applications will be briefly reviewed.
AB - The qualitative detection, quantification, and structural characterization of analytes in biological systems are important requirements for objectives to be fulfilled in systems biology research. One analytical tool applied to a multitude of systems biology studies is mass spectrometry, particularly for the study of proteins and metabolites. Here, the role of mass spectrometry in systems biology will be assessed, the advantages and disadvantages discussed, and the instrument configurations available described. Finally, general applications will be briefly reviewed.
U2 - 10.1016/B978-0-12-385118-5.00002-5
DO - 10.1016/B978-0-12-385118-5.00002-5
M3 - Article
C2 - 21943890
VL - 500
SP - 15
EP - 35
JO - Methods in Enzymology
JF - Methods in Enzymology
ER -