Macroscopic 2D networks self-assembled from nanometer-sized protein/DNA complexes

M Manzanera, DJ Frankel, HT Li, DJ Zhou, A Bruckbauer, P Kreutzmann, JM Blackburn, C Abell, Trevor Rayment, D Klenerman, PD Barker

Research output: Contribution to journalArticle

5 Citations (Scopus)


We demonstrate the self-assembly of DNA and DNA binding proteins into two-dimensional networks that are then addressable by sending a second protein to a specific recognition site on the DNA network. These networks cover centimeters in area but can be addressed with nanometer precision. This hierarchical self-assembly of specific DNA protein complexes will be the basis for complex positioning of single molecules in two and three dimensions.
Original languageEnglish
Pages (from-to)365-370
Number of pages6
JournalNano Letters
Issue number3
Publication statusPublished - 1 Jan 2006


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