Local excision of rectal cancer after neoadjuvant treatment

Johannes H.W. de Wilt; Simon P. Bach

doi:10.1007/978-3-030-58846-5_8

Local excision of rectal cancer after neoadjuvant treatment

Johannes H.W. de Wilt^*, Simon P. Bach

^*Corresponding author for this work

Cancer and Genomic Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Over the past decade, we have observed the emergence of organ preservation treatment for patients with rectal cancer. This trend has developed from two separate sources, firstly, local excision of early stage rectal cancer utilizing platforms such as transanal endoscopic microsurgery (TEM) and, secondly, use of neoadjuvant chemoradiation for treatment of more advanced rectal cancer to achieve complete clinical response (cCR). TEM may be utilized to achieve local resection of small localized rectal tumours, without removing lymph nodes; however, the risk of local recurrence prohibits widespread adoption of this strategy beyond very early-stage disease [1, 2].

Original language	English
Title of host publication	Multidisciplinary Treatment of Colorectal Cancer
Subtitle of host publication	Staging - Treatment - Pathology - Palliation
Publisher	Springer
Pages	55-62
Number of pages	8
ISBN (Electronic)	9783030588465
ISBN (Print)	9783030588458
DOIs	https://doi.org/10.1007/978-3-030-58846-5_8
Publication status	Published - 16 Nov 2020

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2021. All rights reserved.

Keywords

Chemoradiation therapy
Local excision
Radiotherapy
Surgery

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/978-3-030-58846-5_8

Cite this

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AU - Bach, Simon P.

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AB - Over the past decade, we have observed the emergence of organ preservation treatment for patients with rectal cancer. This trend has developed from two separate sources, firstly, local excision of early stage rectal cancer utilizing platforms such as transanal endoscopic microsurgery (TEM) and, secondly, use of neoadjuvant chemoradiation for treatment of more advanced rectal cancer to achieve complete clinical response (cCR). TEM may be utilized to achieve local resection of small localized rectal tumours, without removing lymph nodes; however, the risk of local recurrence prohibits widespread adoption of this strategy beyond very early-stage disease [1, 2].

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KW - Surgery

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BT - Multidisciplinary Treatment of Colorectal Cancer

PB - Springer

ER -

Local excision of rectal cancer after neoadjuvant treatment

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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Cite this