Linked Metabolites: A tool for the construction of directed metabolic graphs.

John Easton, LM Harris, Mark Viant, Andrew Peet, Theodoros Arvanitis

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Metabolic pathway diagrams provide a wealth of information on how reactions combine to perform biological functions. While pathway diagrams are arranged in a way that allows a specific area of metabolism to be visualised, the inherent complexity of each pathway makes it difficult to identify the sets of reactions linking groups of compounds; a common task for researchers attempting to explain observed correlations or looking for further compounds of potential interest to use in validation work. Here we introduce Linked Metabolites, a tool that identifies sets of reactions linking groups of compounds in the context of the KEGG pathway diagrams.
Original languageEnglish
Pages (from-to)340-9
Number of pages10
JournalComputers in Biology and Medicine
Volume40
Issue number3
DOIs
Publication statusPublished - 5 Feb 2010

Keywords

  • KEGG
  • Directed graphs
  • Metabolic pathways
  • All simple paths search
  • Metabolomics

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