TY - JOUR
T1 - Is there a relationship between muscle fatigue resistance and cardiovascular responses to isomentric exerise in mild chronic heart failure
AU - Carrington, Charlotte
AU - Fisher, WJ
AU - Davies, Michael
AU - White, Michael
PY - 2001/1/1
Y1 - 2001/1/1
N2 - Background: Exercise intolerance in chronic heart failure (CHF) may be due to altered fatigue resistance and muscle afferent input to the cardiovascular system from dysfunctional skeletal muscle. Aim: To determine whether calf muscle fatigue resistance was associated with the magnitude of a muscle afferent driven cardiovascular response to isometric exercise. Methods ann results: Cardiovascular responses were recorded in eight stable CHF patients (ejection fraction 20-40%) and nine healthy, age-matched controls during voluntary and electrically evoked isometric plantar flexion and post-exercise circulatory occlusion. The force developed by the plantar flexors during a 2-min submaximal electrically evoked fatigue test was measured. There was no relationship between ischaemic muscle fatigue and cardiovascular changes during and after voluntary contraction in either group nor evoked contraction in the CHF group. In the control group, the change in diastolic blood pressure (DBP) at the end of evoked contraction was related to the severity of fatigue at 90 s and 120 s (FI = 0.01 Delta DBP + 0.3, r = 0.81, P <0.05 and FI = 0.02DBP + 0.8, r = 0.84, P <0.01, respectively). Conclusion: Muscle fatigue resistance did not relate to the magnitude of the cardiovascular stress generated by isometric exercise of the same muscle in these patients. (C) 2001 European Society of Cardiology. All rights reserved.
AB - Background: Exercise intolerance in chronic heart failure (CHF) may be due to altered fatigue resistance and muscle afferent input to the cardiovascular system from dysfunctional skeletal muscle. Aim: To determine whether calf muscle fatigue resistance was associated with the magnitude of a muscle afferent driven cardiovascular response to isometric exercise. Methods ann results: Cardiovascular responses were recorded in eight stable CHF patients (ejection fraction 20-40%) and nine healthy, age-matched controls during voluntary and electrically evoked isometric plantar flexion and post-exercise circulatory occlusion. The force developed by the plantar flexors during a 2-min submaximal electrically evoked fatigue test was measured. There was no relationship between ischaemic muscle fatigue and cardiovascular changes during and after voluntary contraction in either group nor evoked contraction in the CHF group. In the control group, the change in diastolic blood pressure (DBP) at the end of evoked contraction was related to the severity of fatigue at 90 s and 120 s (FI = 0.01 Delta DBP + 0.3, r = 0.81, P <0.05 and FI = 0.02DBP + 0.8, r = 0.84, P <0.01, respectively). Conclusion: Muscle fatigue resistance did not relate to the magnitude of the cardiovascular stress generated by isometric exercise of the same muscle in these patients. (C) 2001 European Society of Cardiology. All rights reserved.
KW - isometric exercise
KW - heart failure
KW - fatigue
UR - http://www.scopus.com/inward/record.url?scp=0035140209&partnerID=8YFLogxK
U2 - 10.1016/S1388-9842(00)00112-4
DO - 10.1016/S1388-9842(00)00112-4
M3 - Article
C2 - 11163736
SN - 1879-0844
VL - 3
SP - 53
EP - 58
JO - European Journal of Heart Failure
JF - European Journal of Heart Failure
IS - 1
ER -