Interventions to prevent miscarriage

Rima K. Dhillon-Smith; Pedro Melo; Rosinder Kaur; Emily Fox; Adam Devall; Natalie Woodhead; Arri Coomarasamy

doi:10.1016/j.fertnstert.2023.08.955

Interventions to prevent miscarriage

Rima K. Dhillon-Smith^*, Pedro Melo, Rosinder Kaur, Emily Fox, Adam Devall, Natalie Woodhead, Arri Coomarasamy

^*Corresponding author for this work

Metabolism and Systems Research

Research output: Contribution to journal › Article › peer-review

Abstract

The physical and psychological impact of miscarriage can be devastating. There are many lifestyle and therapeutic interventions that may prevent a miscarriage. In this review we have outlined the key areas for health optimization to prevent pregnancy loss, drawing on the available up-to-date evidence. The three key areas identified are lifestyle optimization in females, lifestyle optimization in males and therapeutic interventions. The evidence demonstrates that the treatments to consider are first trimester progesterone administration, levothyroxine in women with subclinical hypothyroidism, and the combination of aspirin and heparin in women with antiphospholipid antibodies.

Original language	English
Journal	Fertility and Sterility
Early online date	28 Aug 2023
DOIs	https://doi.org/10.1016/j.fertnstert.2023.08.955
Publication status	E-pub ahead of print - 28 Aug 2023

Keywords

miscarriage
pregnancy loss
interventions

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10.1016/j.fertnstert.2023.08.955

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abstract = "The physical and psychological impact of miscarriage can be devastating. There are many lifestyle and therapeutic interventions that may prevent a miscarriage. In this review we have outlined the key areas for health optimization to prevent pregnancy loss, drawing on the available up-to-date evidence. The three key areas identified are lifestyle optimization in females, lifestyle optimization in males and therapeutic interventions. The evidence demonstrates that the treatments to consider are first trimester progesterone administration, levothyroxine in women with subclinical hypothyroidism, and the combination of aspirin and heparin in women with antiphospholipid antibodies.",

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AU - Dhillon-Smith, Rima K.

AU - Melo, Pedro

AU - Kaur, Rosinder

AU - Fox, Emily

AU - Devall, Adam

AU - Woodhead, Natalie

AU - Coomarasamy, Arri

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AB - The physical and psychological impact of miscarriage can be devastating. There are many lifestyle and therapeutic interventions that may prevent a miscarriage. In this review we have outlined the key areas for health optimization to prevent pregnancy loss, drawing on the available up-to-date evidence. The three key areas identified are lifestyle optimization in females, lifestyle optimization in males and therapeutic interventions. The evidence demonstrates that the treatments to consider are first trimester progesterone administration, levothyroxine in women with subclinical hypothyroidism, and the combination of aspirin and heparin in women with antiphospholipid antibodies.

KW - miscarriage

KW - pregnancy loss

KW - interventions

U2 - 10.1016/j.fertnstert.2023.08.955

DO - 10.1016/j.fertnstert.2023.08.955

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ER -

Interventions to prevent miscarriage

Abstract

Keywords

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