Interaction of epothilone B (patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy

Ashutosh Kumar, Henrike Heise, Marcel J J Blommers, Philipp Krastel, Esther Schmitt, Frank Petersen, Siva Jeganathan, Eva-Maria Mandelkow, Teresa Carlomagno, Christian Griesinger, Marc Baldus

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)7504-7
Number of pages4
JournalAngewandte Chemie (International Edition)
Issue number41
Publication statusPublished - 4 Oct 2010


  • Antineoplastic Agents/isolation & purification
  • Epothilones/isolation & purification
  • Humans
  • Microtubules/metabolism
  • Models, Molecular
  • Myxococcales/chemistry
  • Neoplasms/drug therapy
  • Nuclear Magnetic Resonance, Biomolecular/methods
  • Tubulin/metabolism
  • Tubulin Modulators/isolation & purification

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