Abstract
Oral anticoagulants such as warfarin have been used widely for the treatment of venous thromboembolism and stroke prevention in atrial fibrillation (AF) patients. Warfarin has significant limitations and also requires frequent monitoring. Thus, there is an unmet need, with the quest for alternative oral anticoagulants with stable pharmacokinetics and pharmacodynamics that do not need monitoring. The paper under evaluation provides us with up-to-date information on the safety and efficacy of a new oral anticoagulant, dabigatran, compared with warfarin for stroke prevention in AF patients.
| Original language | English |
|---|---|
| Pages (from-to) | 685-687 |
| Number of pages | 3 |
| Journal | Expert Opinion on Pharmacotherapy |
| Volume | 11 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Mar 2010 |
Keywords
- stroke
- atrial fibrillation
- LDL cholesterol
- Oxidized LDL
- Atheroma score
- direct thrombin inhibitor
- dabigatran
- Ejection fraction
- Apo AI