Inhibition of Src but not Syk causes weak reversal of GPVI-mediated platelet aggregation measured by light transmission aggregometry

Keyphrases

• Platelet Aggregation 100%
• Glycoprotein VI 100%
• Light Transmission Aggregometry 100%
• Spleen Tyrosine Kinase 100%
• GPIIbIIIa 57%
• Tyrosine Phosphorylation 28%
• Bruton's Tyrosine Kinase 28%
• Receptor 2 28%
• Collagen 28%
• C-type Lectin 28%
• Outside-in 28%
• Src Tyrosine Kinase 28%
• Platelets 14%
• Cytoskeleton 14%
• Independent Pathway 14%
• Collagen Peptide 14%
• Indomethacin 14%
• Kinase Inhibition 14%
• Src Kinase 14%
• Fluorescein Isothiocyanate 14%
• Glycoprotein IIb-IIIa 14%
• Light Transmission 14%
• Integrin Activation 14%
• Src Kinase Inhibitor 14%
• PAC1 14%
• Rhodocytin 14%
• Kinase-independent 14%
• Labeled Antibody 14%
• Apyrase 14%
• Eptifibatide 14%
• Spleen Tyrosine Kinase Inhibitor 14%
• Time Aggregation 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Glycoprotein VI 100%
• Janus Kinase 1 100%
• Protein Kinase Syk 100%
• Receptor 42%
• Fluorescein Isothiocyanate 28%
• Lectin 28%
• Bruton Tyrosine Kinase 28%
• Protein Tyrosine Kinase 14%
• Phosphotransferase 14%
• Indometacin 14%
• Integrin 14%
• Fibrinogen Receptor 14%
• Apyrase 14%
• Eptifibatide 14%
• Protein Kinase Syk Inhibitor 14%

Biochemistry, Genetics and Molecular Biology

• Glycoprotein 100%
• Thrombocyte Aggregation 100%
• Janus Kinase 1 100%
• Tyrosine Phosphorylation 25%
• C-Type Lectin 25%
• Bruton Tyrosine Kinase 25%
• Platelet 12%
• Tyrosine 12%
• Kinase 12%
• Phosphotransferase 12%
• Cytoskeleton 12%
• Independent Pathway 12%
• Glycoprotein IIb/IIIa 12%
• Fluorescein Isothiocyanate 12%
• Apyrase 12%
• Tyrosine Kinase Inhibitor 12%
• Eptifibatide 12%
• Integrin 12%